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P53、Bcl-2、MDM2和P21在口腔鳞状细胞癌中的表达及相关研究 被引量：3

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摘要 鳞状细胞癌是口腔中最常见的恶性肿瘤（约占口腔癌瘤80%以上）,其生物学行为较为特殊,难以预测。研究表明,鳞状细胞癌是多基因性的疾病,在其发生发展过程中有多种基因参与调控,包括原癌基因的激活和抑癌基因的失活。其中P53、Bcl一2、MDM2和P21基因与鳞状细胞癌的发生、发展有密切关系，它们在口腔鳞状细胞癌（OSCC）的发生发展中既互相影响，又相对独立，因此，通过对上述基因不断深入地研究可为OSCC的治疗提供新思路。
作者 郭珍珍 陈作良
机构地区 福建医科大学口腔医学院 厦门市口腔医院
出处 《福建医药杂志》 CAS 2012年第4期144-145,共2页 Fujian Medical Journal
关键词 P53基因 BCL-2基因 MDM2基因 P21基因 口腔鳞状细胞癌
分类号 R739.8 [医药卫生—肿瘤] R446 [医药卫生—诊断学]
  • 相关文献

参考文献13

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二级参考文献12

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共引文献2

同被引文献21

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引证文献3

二级引证文献10

福建医药杂志
2012年 第4期

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