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蒽环类药物治疗儿童急性白血病的现状及进展 被引量:3

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摘要 蒽环类药物是最有效的抗肿瘤药物之一。第一代蒽环类药物是上世纪60年代从波赛链霉菌中分离出来的,并命名为柔红霉素(DNR)和阿霉素(多柔比星,DOX)。DNR和DOX分子结构上的唯一区别是,DNR的一个支链为甲基基团,而DOX为乙醇基基团,见图1。
出处 《中国小儿血液与肿瘤杂志》 CAS 2013年第1期5-7,共3页 Journal of China Pediatric Blood and Cancer
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  • 1Weiss RB. The anthracyclines:will we ever find a better doxorubicin[J].Seminars in Oncology,1992.670-686.
  • 2Danesi R,Fogli S,Gennaii A. Pharmacokinetic pharmacodynamic relationships of the anthracycline anticancer drugs[J].Clinical Pharmacokinetics,2002.431-444.
  • 3Borchmann P,Hübel K,Schnell R. Idarubicin:a brief overview on pharmacology and clinical use[J].International Journal of Clinical Pharmacology and Therapeutics,1997.80-83.
  • 4Andeilini P,Benjamin RS,Wong FC. Idarubicin cardiotoxicity:a retrospective study in acute myeloid leukemia and myelodysplasia[J].Journal of Clinical Oncology,1995.2827-2834.
  • 5Kudo K,Kojima S,Tabuchi K. Prospective study of a pirarubicin,intennediate-dose cytarabine,and etoposide regimen in children with Down syndrome and acute myeloid leukemia:the Japanese Childhood AML Cooperative Study Group[J].Journal of Clinical Oncology,2007.5442-5447.
  • 6Gibson BE,Webb DK,Howman AJ. Results of a randomized trial in children with Acute Myeloid Leukaemia;medical research council AML12 trial[J].British Journal of Haematology,2011.366-376.
  • 7Parker C,Waters R,Leighton C. Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL,R3):an open-label randomised trial[J].Lancet,2010.2009-2017.
  • 8Barry E,Alvarez JA,Scully RE. Anthracycline-induced cardiotoxicity:course,pathophysiology,prevention and management[J].Expert Opinion on Pharmacotherapy,2007,(8):1039-1058.doi:10.1517/14656566.8.8.1039.
  • 9Swain SM,Whaley FS,Ewer MS. Congestive heart failure in patients treated with doxorubicin:a retrospective analysis of three trials[J].Cancer,2003,(11):2869-2879.
  • 10Blanco JG,Sun CL,LandierW. Anthracycline-related cardio-myopathy after childhood cancer:role of polymorphisms in carbonyl reductase genes-a report from the Children's Oncology Group[J].Journal of Clinical Oncology,2012.1415-1421.

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