摘要
目的探讨度洛西汀合并心理治疗对产后抑郁症的临床疗效及安全性。方法将69例产后抑郁症患者随机分为A组35例,B组34例,两组均给予度洛西汀治疗,A组联合心理治疗,疗程6周。于治疗前及治疗1、2、4、6周末采用汉密顿抑郁量表(HAMD17)评定临床疗效,用不良反应量表(TESS)评估不良反应和安全性。结果汉密顿抑郁量表评分治疗第2周末起两组均较治疗前有极显著性下降(t=13.33,8.05;P<0.01);两组同期评分比较A组较B组下降更显著(t=11.56,3.68,7.95,4.23;P<0.01);两组不良反应无显著性差异。结论度洛西汀联合心理疗认知疗法治疗产后抑郁症疗效显著,安全性高,依从性好。
Objective To explore the efficacy and safety of duloxetine combined psychotherapy in the treatment of postpartum depression.Methods A total of 69 patients with postpartum depression were divides into A group（35 examples）and B group（34 examples）,they took duloxetine,and patients in A group received psychotherapy,the treatment time was 6 weeks.Using the Hamilton rating scale for depression to assess clinical efficacy,and Treatment Emergent Symptom scale（TESS）wase used to assess safety.Results The scores of HAMD in both groups were significantly decreased in 2 weeks after treatment（t=13.33,8.05;P0.01）.there were significant differences in HAMD between two groups（t=11.56,3.68,7.95,4.23;P0.01）,and no significant differences in side effect（P0.05）.Conclusion Doloxetine combined psychotherapy has good efficacy in the treatment of postpartum depression,which has high safety and good compliance.
出处
《中国健康心理学杂志》
2013年第2期193-195,共3页
China Journal of Health Psychology
