摘要
目的：探索蛋白琥珀酸铁与富马酸亚铁治疗妊娠期缺铁性贫血的临床疗效差异。方法：选择2009年3月-2011年3月在笔者所在医院围产门诊行围产保健的妊娠12—20周的120例孕妇，随机分为研究组60例，给予蛋白琥珀酸铁片口服纠正贫血，对照组60例，171服富马酸亚铁片，两组孕妇于治疗前、治疗后6周检测并记录血常规及铁代谢的各项指标变化、疗效及耐受性。结果：治疗6周后研究组与对照组之间红细胞及铁代谢指标比较差异无统计学意义（P〉0．05）。使用蛋白琥珀酸铁的孕妇无一例发生不良反应，但是在口服富马酸亚铁5周后，对照组出现8例明显的不良反应。结论：蛋白琥珀酸铁与富马酸亚铁片用于治疗妊娠缺铁性贫血效果良好，能有效缓解妊娠期缺铁性贫血的临床症状和实验室指标，但是蛋白琥珀酸铁较富马酸亚铁片不良反应少，耐受性好，可长期使用。
Objective： To explore clinical efficacy differences of iron protein succinylate and ferrous fumarate treatment of iron deficiency anemia during pregnancy.Methods： From March 2009 to March 2011 in author＇s hospital perinatal patient line of perinatal health care of pregnant women in 120 cases of pregnancy in 12-20 weeks pregnant randomly divided into the study group 60 cases, were given proteinsuccinylate oral iron for correction of anemia, 60 cases in the control group were given oral ferrous fumarate tablets, the blood and iron metabolism indices change, efficacy and tolerability of the pregnant women of two groups before treatment, after treatment 6 weeks were detected and recorded.Results： After 6 weeks treatment, study group and the control group between erythrocyte and iron metabolism index showed no significant difference （P〉O.05）.The use of iron proteinsuccinylate pregnant women with no adverse reactions, in the oral ferrous fumarate, but after 5 weeks, the controi group 8 cases with adverse reaction.Conclusion： Iron proteinsuccinylate and ferrous fumarate tablets for treatment of iron deficiency anemia in pregnancy with good effect, can effectively alleviate iron deficiency anemia during pregnancy clinical symptoms and laboratory indexes, but iron proteinsuccinylate have fewer adverse reactions than ferrous fumarate tablets, can be well tolerated, long term use.
出处
《中外医学研究》
2013年第4期1-2,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
蛋白琥珀酸铁
富马酸亚铁片
妊娠期缺铁性贫血
Iron Proteinsuccinylate
Ferrous fumarate tablets
Iron deficiency anemia during pregnancy
