摘要
【目的】探讨宫颈液基薄层细胞学（TCT）联合阴道镜在筛查宫颈癌前病变中的诊断价值。【方法】选择2005年1月至2012年1月在本院妇科门诊采用TCT和阴道镜检查筛查宫颈癌前病变的患者982例，同时在阴道镜下对患者宫颈进行多位点活检送病理检查。以组织病理学检查为金标准，分析TCT和阴道镜在筛查宫颈癌前病变中的诊断价值。【结果】在982例妇女中，TCT细胞学检查出异常者有118例，对诊断宫颈上皮内瘤样变（CIN）的特异性为96．5l％，敏感性为58．55％，漏诊率为6．42％；阴道镜检查出异常者有163例，对诊断CIN的特异性为97．47％，敏感性为93．42％，漏诊率为1．02％；TCT联合阴道镜检查，其诊断CIN的特异性为98．80％，敏感性为96．03％，漏诊率为0．71％。【结论]TCT联合阴道镜检查能提高宫颈癌前病变的检出率，能较早期筛查出宫颈癌前病变，从而有利于早期诊断和早期治疗，提高患者的生存率。
[Objective] To explore the value of liquid-based cytology test（TCT） combined with colposcopy in the screening of cervical precancerous lesions. [Methods] Totally 982 patients with cervical precancerous lesion receiving TCT and eolposcopy screening in clinic service of our gynecology department in our hospital from Jan. 2005 to Jan. 2012 were chosen. Multiple-site biopsy of cervixes of patients under colposcope was performed for pathological examination. The histopathology examination was used as the gold standard. The value of TCT and colposcopy in the diagnosis of cervical lesions was analyzed. [Results] Among the 982 females, 118 females were abnormal detected by using TCT. The speci ficity, sensitivity and missed diagnosis rate of TCT for the diagnosis of cervical intraepithelial neoplasia（CIN） were 96.51%, 58.55% and 1.02%, respectively. The 163 females were abnormal detected by using colposcopy, and the spe cificity, sensitivity and missed diagnosis rate for CIN were 97.47%, 93.42% and 1.02%, respectively. Furthermore, the specificity, the sensitivity and missed diagnosis rate of the combination of TCT and colposcopy for CIN were 98.80%, 96.03 % and 0.71%, respectively. [Conclusion] TCT combined with colposcopy can increase the detection rate of cervical precancerous lesion, and earlier screen out cervical precancerous lesions. Thus it is helpful for early diagnosis and treat ment, and can improve the survival rate of patients.
出处
《医学临床研究》
CAS
2013年第1期72-74,共3页
Journal of Clinical Research
关键词
宫颈肿瘤
癌前状态
阴道镜检查
uterine cervical neoplasms
precancerous conditions
colposcopy
