摘要
目的对过敏性疾病儿童进行血清特异性IgE抗体检测,筛选相关过敏原,为临床诊断和治疗提供依据。方法运用AllergyScreen过敏原检测系统对350例过敏性疾病儿童进行血清特异性IgE定量检测。结果 350例过敏患儿14种过敏原检测过敏原阳性率为57.71%。在14种过敏原中,尘螨的阳性例数最多,其次为牛奶、猫狗毛皮屑及鸡蛋白,蟑螂、真菌、牛肉、羊肉。男女性别组过敏原阳性率比较,差异无统计学意义(P>0.05)。吸入过敏学龄前儿童和学龄儿童均高于婴幼儿,差异均有统计学意义(P<0.05),食入过敏婴幼儿高于学龄前儿童和学龄儿童,差异均有统计学意义(P<0.05),婴幼儿组内食物过敏高于吸入,差异有统计学意义(P<0.05),学龄前儿童和学龄儿童组吸入过敏均高于食物,差异均有统计学意义(P<0.05)。结论泉州地区儿童过敏性疾病最主要的过敏原为尘螨,其次为牛奶、猫狗毛皮屑及鸡蛋白。不同性别间过敏原阳性率差别无统计学意义。不同年龄儿童过敏原结构不完全相同。
Objective To detect specificity serum IgE antibody from children with allergic diseases,then to screen related allergens in order to provide a scientific evidence in the diagnosis and treatment of children with allergic diseases. Methods The specificity serum IgE antibody of 350 children with allergic diseases were detected quantita- tively by allergy screen allergens test system. Results The positive rate of 14 kinds of allergens in 350 children with allergic diseases was 57.71%. Among the 14 kinds of allergens, the amount of children with positive dust mites was the highest, followed by milk and cat fur, dog fur and chicken egg protein. Cockroaches, mould, beef and mutton also took a rather high ratio of it. There was no significant difference in the positive rate of allergens between boys and girls（P〉0.05）. In inhalant allergen group,the positive rate of allergens in pre-school children and school-age chil- dren were all significantly higher than that of infants（P〈0.05）. In food allergen group, the positive rate of allergens in infants was significantly higher than that in pre-school children and school-age children（P〈0.05）. Among the in- fants, the positive rate of allergens in food allergen group was significantly higher than that in inhalant allergen group （P〈0.05） ;Among the pre-school children and school-age children, the positive rates of allergens in inhalant allergen group were all significantly higher than that in food allergen group（P〈0. 01）. Conclusion The main allergen in Quanzhou region is dust mite,followed by milk and cat fur, dog fur and chicken egg protein;There is no significant difference of the positive rate of allergens between boys and girls. The children at different ages have different compositions of allergens.
出处
《检验医学与临床》
CAS
2013年第4期435-436,438,共3页
Laboratory Medicine and Clinic
关键词
过敏性疾病
特异性过敏原
儿童
allergic diseases
specific allergens
children
