摘要
目的:观察黛力新联合胃食管反流病(gastroesophageal refluxdisease,GERD)标准治疗在质子泵抑制剂无效且伴有抑郁、焦虑的糜烂性食管炎(erosive esophagitis,EE)患者的临床疗效。方法:对按GERD标准正规治疗无效的44例EE患者在给予兰索拉唑、硫糖铝混悬凝胶及多潘立酮片常规治疗同时加服氟哌噻吨美利曲辛10.5mg,1次/d,治疗6周后判定疗效。结果:治疗6周后,44例患者烧心、胸痛、反酸等症状均有明显减轻,治疗显效38例,有效4例,显效率为86.4%(38/44),总有效率为95.5%(42/44)。结论:对质子泵抑制剂无效的伴抑郁与焦虑的糜烂性食管炎患者,联合黛力新治疗,可快速减轻糜烂症状,改善患者的抑郁与焦虑,值得推广。
Objective： To observe the clinical effect of the treatment for patients, who had erosive esophagitisdisease （EE） associated with depression and anxiety with proton pump inhibitor treatment failures, using Lansoprazole united Deanxit.Methods： 44 patients with EE were given additionally Deanxit （10.5 mg, once a day）for 6 weeks with general treatment.Results： All patients recovered and the treatment rate of the 44 patients was 86.4%（38/44）, with the total effective rate of 95.5%（42/44）.Conclusion： Deanxit joint anti-reflux treatment can quickly relieve reflux symptoms and improve the patient＇s depression and anxiety, it should be recommended.
出处
《中外医学研究》
2013年第5期11-12,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
糜烂性食管炎
黛力新
抑郁
焦虑
Erosive esophagitis
Deanxit
Depression
Anxiety
