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龈下刮治配合补肾固齿丸治疗中、重度牙周炎的短期疗效评价 被引量:11

Efficacy evaluation of subgingival scaling with Bushenguchiwan in short-term treatment of moderate to severe periodontitis
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摘要 目的:探讨龈下刮治配合补肾固齿丸对中、重度牙周炎的短期治疗效果。方法:纳入中、重度牙周炎患者共44例,随机分为两组,每位患者选择2颗指数牙。所有患者试验前均进行龈上洁治和龈下刮治,试验组同时给予口服补肾固齿丸4 g/次,2次/日,连服3个月。测定治疗前后指数牙的探诊出血(BOP)、探诊深度(PD)、附着丧失(AL)及其牙槽骨平均灰度值(MGVs)。结果:试验组BOP阳性率、PD和AL均较治疗前有明显下降(P<0.05),而MGVs升高(P<0.05)。对照组治疗后BOP阳性率和PD明显降低(P<0.05),但AL及MGVs无明显改善(P>0.05)。试验组与对照组对中、重度牙周炎的短期疗效有显著差异(P<0.05)。结论:龈下刮治配合口服补肾固齿丸治疗中、重度牙周炎的短期疗效明显优于单纯龈下刮治组,可能与补肾固齿丸能促进牙槽骨新骨形成、降低AL有关。 Objective: To evaluate the effect of subgingival scaling with Bushenguchiwan on short-term treatment of moderate to severe periodontitis. Method:44 moderate to severe periodontitis patients were enrolled into this trial,whom were randomly divided into two groups, 23 in the experimental group and 21 in the control group. Each patient with 2 index teeth were selected. Every patient in this study was given periodontal initial therapy, including supragingival scaling and sub- gingival scaling. After that, patients in the experimental group took 4 g Bushenguchiwan orally twice a day for 3 months. Bleeding on probing (BOP), probing depth (PD), attachment loss (AL) and mean grey values (MGVs) of the alveolar bone of all teeth which were selected were measured before and after treatment. Result: After 3 months treatment, the ratio of BOP (+), PD and AL in the experimental group were decreased significantly (P 〈0.05), while MGVs were significantly increased (P 〈0.05). The ratio of BOP (+) and PD in the control group showed the same change as in the experimental group. However, AL and MGVs in the control group showed positive change (P 〉0.05). The total efficacy ratio of the experimental group was higher than that of the control group, with significantly difference (P 〈0.05). Conclusion: The effect of subgingival scaling with Bushenguchiwan on short-term treatment of moderate to severe periodontitis is obviously superior to simple scaling. The effect may be associated with Bushenguchiwan which could promote alveolar bone formation and decrease AL.
出处 《临床口腔医学杂志》 2013年第2期117-119,共3页 Journal of Clinical Stomatology
基金 广东省中医药局2011年建设中医药强省科研课题(20112013)
关键词 补肾固齿丸 重度牙周炎 龈下刮治 Bushenguchiwan moderate to severe periodontitis: subgingival scaling
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