摘要
目的探讨桂哌齐特对急性脑梗死患者血清超敏c反应蛋白（hs—CRP）和S100B蛋白（S100B）的影响。方法将90例急性脑梗死患者随机分为对照组45例和治疗组45例。对照组采用常规治疗，治疗组加用桂哌齐特注射液治疗，两组均治疗14d。治疗前后测定患者血清hs—CRP和SIOOB。结果治疗组总有效率为93．3％，高于对照组的84．4％（X^2=4．0125，P〈0．05）。两组治疗后均可明显降低血清hs—CRP和SIOOB（均P〈0．05），并且治疗组降低更明显（均P〈0．05）。结论桂哌齐特通过减轻炎性反应而缓解急性脑梗死患者的病情。
Objective To explore the influence of Gui piperazine strange maleate on the high sensitive C-re- active protein（hs-CRP） and S100B in the serum of patients with acute cerebral infarction. Methods 90 patients with acute cerebral infarction were randomly divided into two groups, the control group（45 cases） and the treatment group （45 cases）. The patients in the control group were treated through the conventional treatment,while the patients in the treatment group were treated plus Gui piperazine strange maleate. They were treated for fourteen days. The hs-CRP and S100B in the serum were detected before and after treatment. Results The total effective rates were 93.3% in the treatment group and 84.4% in the control group. There was a significant difference between two groups（ X2 =4. 0125, P 〈 0.05 ）. The hs-CRP and S100B were decreased after treatment in both groups （ all P 〈 0.05 ） , and there was a sig- nificant difference between two groups after treatment （ all P 〈 0.05 ）. Conclusion Gui piperazine strange maleate can improve acute cerebral infarction through, mitigating inflammation.
出处
《中国基层医药》
CAS
2013年第4期522-524,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
脑梗死
超敏C反应蛋白
S100蛋白
桂哌齐特
Cerebral infarction
High sensitive C-reactive protein
S100B
Gui piperazine strange maleate
