摘要
目的探讨尿微量白蛋白与妊娠期高血压疾病早期肾损害相关性。方法选取126例妊娠期高血压疾病患者作为观察组，选取同期健康孕妇100例作为对照组，检测两组孕妇尿微量白蛋白含量并比较。结果观察组尿微量白蛋白含量为（34．86±18．41）mg／L，阳性56例，阴性70例，对照组尿微量白蛋白含量为（18．64±16．45）mg／L，阳性12例，阴性88例，两组尿微量白蛋白含量及阳性率差异均有统计学意义（t=6．89，X^2=27．90，均P〈0．05）；观察组尿微量白蛋白阳性患者与阴性患者收缩压分别为（155．6±18．4）minHg、（146．3±18．7）mmHg，差异有统计学意义（t=2．79，P〈0．05）。结论在妊娠期进行尿微量白蛋白检测，可以有效确定妊娠期高血压疾病患者是否存在早期肾损害，有助于判断妊娠期高血压疾病的病情严重程度。
Objective To explore the corelations between trace protein in urine and early kidney damage in gestational hypertension disease. Methods 126 patients with gestational hypertension disease were selected as the observation group, and 100 cases of healthy pregnant women over the same period were selected as the control group＂ The urinary albumin content of pregnant women in the two groups was detected and compared. Results In the obser- vation group, the content of urinary albumin was （34.86 ± 18.41 ） mg/L, and positive patients in 56 cases, negative in 70 cases. In the control group, the content of urinary albumin was （ 18.64 ± 16.45 ） mg/L, and positive patients in 12 cases, negative in 88 cases. The differences of the urinary albumin content and positive rates between the two groups were statistically significant（t = 6.89 ,X2 = 27.90, all P 〈0.05 ） ;The systolic blood pressure of urinary albumin-posi- tive patients and negative patients in the observation groups were （155.6 ± 18.4）mm Hg, （146.3 ± 18.7 ）mm Hg, respectively, and the difference was statistically significant （t = 2.79, P 〈 0.05 ）. Conclusion Urinary albumin tes- ting during pregnancy can effectively determine the existence of early renal damage in patients with gestational hyper- tension disease, and it can help to judge the severity of gestational hypertension disease.
出处
《中国基层医药》
CAS
2013年第4期544-545,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
尿微量白蛋白
妊娠期高血压疾病
早期
肾损伤
Urinary albumin
Gestational hypertension disease
Early, renal injury
