摘要
将SD大鼠随机分为5组,灌胃2个月后,常规方法制备大鼠血清及肝匀浆,测定血清中谷草转氨酶(sGOT)、谷丙转氨酶(sGPT)、碱性磷酸酶(sALP)、γ-谷氨酰转肽酶(γ-GGT)、血糖、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及肝匀浆中丙二醛(MDA)、谷胱甘肽(GSH)的含量,以此探讨不同用量的梅兰春芝麻香型白酒(MSL)对大鼠血脂、血糖和肝功能的影响。结果表明,空白对照组的sGPT、γ-GGT高于其他剂量组;高剂量组sALP高于空白对照组和低剂量组;高剂量组TG高于低剂量组;高剂量组血糖高于空白对照组;空白对照组、高剂量组GSH高于其他剂量组;MDA含量随白酒用量的增加而增加。推断出饮用量低于1.43 mL/(kg·d)的42%vol梅兰春芝麻香型白酒有益于健康,高于2.86 mL/(kg·d)则会对机体产生不良作用。
In order to study the effects of drinking different doses of Meilanchun sesame-flavor liquor on blood lipid, blood glucose and liver functions in rats, 50 SD rats were randomly divided into 5 groups. SD rats in different dosage groups were administered with Meilanchun sesame-flavor liquor for two months. The levels of glutamic-oxalacetic transaminease （sGOT）, glutamate pyruvate transaminase （sGPT）, alkaline phosphatase （sALP）, γ-glutamyl tmnspeptidase （γ-GGT）, blood glucose, total cholesterol （TC）, total triglycerides （TG）, high-density lipoprotein （HDL-C）, low-density lipoprotein （LDL-C） in serum and the content of glutathione （GSH）, malondialdehyde （MDA） in liver were detected. The results were summed up as follows： sGPT and γ-GGT in control group were higher than other dosage groups; sALP and TG in high dose group were higher than low dose group; compared with control group, sALP and blood glucose in high dose group was higher; GSH in control group and high dose group was higher than other groups; and MDA content increased with the increase of dosage. It was concluded that drinking Meilanchun sesame-flavor liquor （less than 1.43 mL/ （kg-d）） is beneficial to health, however, drinking the liquor more than 2.86 mL/ （kg. d） is harmful.
出处
《酿酒科技》
北大核心
2013年第2期46-49,共4页
Liquor-Making Science & Technology
基金
江苏省企业研究生工作站基金(苏教研[2012]4号)
