摘要
目的针对当前中医方药量效关系研究的缺乏和用药安全性监测存在不足的现状,提出中医方药剂量相关安全性评价平台的构建及其方法。方法在中医药理论的指导下,加强方药剂量相关的安全性研究,研制具有中医特色的、基于患者报告的方药不良反应/事件监测量表,用于开展方药剂量相关的主动前瞻性评价示范研究,在建立和完善方药不良反应/事件数据库的基础上,采用信息化手段,研制安全性监测模块,形成方药剂量相关的安全性网络。结果与结论在以上工作的基础上,构建方药剂量相关安全性评价平台。
OBJECTIVE To put forward a method of construction of the safety evaluation platform related to formula-medicine dose of TCM because of the lack of the dose-effect relationship research and the insufficient of safety monitoring in Chinese medicine. METHODS Under the guidance of Chinese medicine theory, an ADR（adverse drug reaction） /ADE（adverse drug event） monitoring scale with TCM characteristics was developed based on patients reporting, thus to promote positive and prospective evaluation resear- ches related to formula-medicine dose. On the basis of the ADR/ADE data base, the safety monitoring module will be formed then. RESULTS AND CONCLUSION The safety evaluation platform related to formula-medicine dose is supposed to he structured.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2013年第5期346-348,共3页
Chinese Pharmaceutical Journal
基金
国家重点基础研究发展计划(973计划)项目(2010CB530601)
关键词
方药
剂量相关
安全性评价平台
formula- medicine
does-related
safety monitoring platform
