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慢性肾脏病3期肾虚证证候研究 被引量:8

Study on the kidney deficiency syndrome in patients with chronic kidney disease-3 stage
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摘要 目的:探讨慢性肾脏病3期(CKD3期)肾虚证的证候。方法:观察和分析411例CKD3期患者肾虚证的分布特点、症状特征以及肾虚证与其他证候的兼挟情况。结果:95.13%CKD3期患者存在肾虚证,88.98%的肾虚证与风湿证、肾络瘀痹证呈二、三联合并存在;肾虚证主要表现为腰酸、乏力、泡沫尿、夜尿、头晕耳鸣等症状;肾虚证积分高者并存瘀痹证的腰痛固定、肢体麻木、肌肤甲错的症状分值及瘀痹证的证候总积分相对高,且并存风湿证候的泡沫尿、恶风等症状积分和风湿证候总积分亦相对高,比较均具有显著差异(P<0.01,P<0.05)。结论:肾虚证是CKD3期最主要证候,多与风湿证、肾络瘀痹证呈二、三联证存在,肾虚证的程度与风湿证、肾络瘀痹证的程度密切相关。 Objective: To explore the characteristics of the syndrome of deficiency of kidney-Qi and Yin (blood) in patients with chronic kidney disease-3 stage (CKD-3 stage). Methods: Observe and analyze the distribution and characteristics of deficiency syndrome in 411 patients with chronic kidney disease-3 stage, and the frequency and intensity of various syndromes. Explore the correlations between deficiency syndrome and other syndromes. Results: 95.13% of the patients with CKD-3 stage had deficiency syndrome, meanwhile 88.98% of the patients had the deficiency syndrome together with wind-dampness syndrome and/or blood stasis syndrome. Patients with deficiency syndrome often displayed symptoms of soreness in waist area, fatigue, nocturnal enuresis, dizziness and tinnitus. Patients with higher score of deficiency syndrome had higher scores of wind-dampness syndrome and/or blood stasis syndrome. They had significant difference (P〈0.01, P〈0.05). Conclusion: Deficiency syndrome is the main syndrome in the CKD-3 stage, and it always coexists with blood stasis or/and wind-dampness syndrome. The severity of deficiency syndrome is closely related to wind-dampness syndrome and blood stasis syndrome.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2013年第3期695-698,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 "十一五"国家科技支撑计划项目(No.2006BAI04A07)~~
关键词 慢性肾脏病3期 肾虚证 证候 Cr, D-3 stage Kidney deficiency syndrome TCM syndrome
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