摘要
bHLH(basic helix-loop-helix protein)是真核生物中存在最广泛的一大类转录因子,其通过特定的氨基酸残基与靶基因相互作用,进而调节相关基因的表达。系统发育分析表明植物的bHLH转录因子为单源进化。bHLH转录因子不仅对于植物的正常生长和发育必不可缺,同时参与植物适应多种逆境胁迫的反应过程。然而,由于植物bHLH家族成员众多、参与的生物过程复杂,对于其了解还不是十分清楚。本文针对植物bHLH的进化、结构特点、生物功能,尤其是在适应逆境胁迫中作用等的最新研究结果进行综述,以期为进一步深入了解植物bHLH转录因子的功能提供理论参考。
Basic helix-loop-helix proteins （bHLHs） are found throughout the eukaryotic kingdom, and constitute one of the largest families of plant transcription factors. They can regulate gene expression through interaction with specific motif in target genes. Phylogenetic analysis indicates that plant bHLHs are monophyletic, bHLHs are necessary for plant normal growth and development, and play important roles in abiotic-stress responses. However, we know little about their origins, structures, and functions due to the large quantities and complexity of plant bHLH family. This paper reviews on the evolution, structure characteristics, biological function of plant bHLHs, especially their functions in adapting to abiotic-stress tolerance, so as to provide a theoretical reference for further research on the function of plant bHLH transcription factors.
出处
《生物技术进展》
2013年第1期7-11,共5页
Current Biotechnology
基金
国家自然科学基因项目(30970221)资助
关键词
BHLH
结构特点
生物学功能
bHLHs
structural features
biological function
