摘要
目的探讨血清中α1-微球蛋白(α1-MG)、同型半胱氨酸(Hcy)和胱抑素C(Cys C)在2型糖尿病肾病(DN)患者检测中的意义。方法 2011年3月至2012年2月检测97例2型糖尿病患者和32例健康对照者血清α1-MG、Hcy、Cys C水平变化。其中糖尿病患者分为临床糖尿病肾病组(A组)33例,早期糖尿病肾病组(B组)35例和单纯糖尿病组(C组)29例。结果糖尿病组血清α1-MG、Hcy、Cys C水平明显高于健康对照组(P<0.05);并且,血清α1-MG、Hcy和Cys C水平在C、B组和A组逐渐增高,各组间比较差异有统计学意义(P<0.05)。结论 DN患者血清α1-MG、Hcy和Cys C水平明显升高,并且其与病情的发展密切相关。
Objective To investigate the significance of serum αl- microglobulin（αl-MG） ,homocysteine（Hcy） and cystatin C（Cys C） detection in type 2 diabetic patients with nephropathy（DN）. Methods The changes of serum αl-MG, Hcy and Cys C levels were detected in 97 patients with type 2 diabetes and 32 healthy controls from March 2011 to February 2012. The diabetic patients were divided into the clinical diabetic nephropathy group（group A, 33 cases） ,the early diabetic nephropathy group（group B, 35 cases） and the simple diabetic group（group C, 29 cases）. Results Serum αl-MG, Hcy and Cys C levels in the diabetic group were significantly higher than those in the control group（P〈0.05）. Serum αl-MG, Hcy and Cys C levels in the group C, B and A groups were increased gradually, sta- tistical difference existed among various groups（P〈0.05）. Conclusion Serum αl-MG, Hcy and Cys C in DN patients are significantly increased, which is closely related with the disease progress.
出处
《检验医学与临床》
CAS
2013年第5期532-533,共2页
Laboratory Medicine and Clinic
