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初诊为脂溢性角化病的Leser-Trelat征一例 被引量:2

Seborrheic Keratosis with Leser-Trelat Sign Associated with Lung Cancer:A Case Report
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摘要 Leser-Trelat征是指成年人突然出现大量瘙痒性脂溢性角化皮损合并内脏恶性肿瘤的征象。如果脂溢性角化病患者皮损短期内出现体积增大、数量增多并伴瘙痒,常提示内脏肿瘤,应进行相关排癌检查,特别是皮损的表皮生长因子免疫组化分析。本文就1例脂溢性角化病的Leser-Trelat征合并肺癌患者的诊治过程进行报道,以提高临床医师对该病的认识。 Leser - Trelat sign is characterized by the abrupt appearance of multiple seborrheic keratoses combined with internal malignancy. If seborrhoeic keratoses have rapid increase in size and number combined with pruritus, it usually indicates internal cancer, and relevant screening test should be conducted, especially immunohistochemical analysis on epidermal growth factor of the keratoses. This paper reports a case of seborrheic keratosis with Leser - Trelat sign combined with lung cancer in order to strengthen the understanding of this disease by clinical physicians.
出处 《中国全科医学》 CAS CSCD 北大核心 2013年第6期701-703,共3页 Chinese General Practice
关键词 角化病 脂溢性 Leser—Trelat征 肺肿瘤 Keratosis, seborrheic Leser - Trelat sign Lung neoplasms
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参考文献6

  • 1Mittal RR, Sonal J. The sign of Leser - Trelat [ J ] . India J Dermatol Venereol Leprol, 2001, 67 (4) : 177.
  • 2Lynch HT, Fusaro RM, Pester JA, et al. Leser - Trelat sign in mother and daughter with breast cancer [J].J Med Genet, 1982, 19(3) : 218 -221.
  • 3Safa G, Darrieux L. Leser - Tr61at sign without internal malignancy [ J ] . Case Rep Oncol, 2011, 4 (1): 175-177.
  • 4Tajima H, Mitsuoka S, Ohtsuka E, et aL A case of hepatocellular carcinoma with the sign of Leser - Trelat: a possible role of a cutane- ous marker for internal malignancy [ J] . Jpn J Med, 1991, 30 (1): 53-56.
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同被引文献7

  • 1赵辨.中国临床皮肤病学[M].南京:江苏科学技术出版社,2009,12:744.
  • 2Lynch HT, Fusaro RM, Pester JA, et al. Leser-Trelat sign in mother and daughter with breast cancer [ J ]. J Med Genet, 1982,19 (3) :218 - 221.
  • 3Turan E, Yesilova Y, Yurt N, et al. Leser-Tr61at sign: does it really exist.9 [ J 1- Acta Dermatovenerol Croat, 2013,21 (2) :123 - 127.
  • 4Safa G, Darrieux L. Leser-Tr61at sign without internal malignancy [ J ]. Case Rep Oncol, 2011,4 ( 1 ) : 175 - 177.
  • 5Silva JA, Mesquita Kde C, Igreja AC, et al. Paraneoplas- tic cutaneous manifestations : concepts and updates [ J l- An Bras Dermatol,2013,88( 1 ) :9 -22.
  • 6郑晶琼,吴国民,虞义建.莱泽-特雷拉综合征[J].中国耳鼻咽喉头颈外科,2010,17(1):47-47. 被引量:2
  • 7李其爱,晏洪波,冯俊明,马利尔,张晶.Leser-Trélat征并发前列腺癌1例[J].临床皮肤科杂志,2013,42(10):611-612. 被引量:1

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