摘要
目的探讨电视胸腔镜手术(VATS)治疗胸部肿瘤的临床效果。方法 52例胸部肿瘤患者分成2组,对照组26例给予传统开胸术治疗,观察组26例给予VATS治疗;观察比较2组患者的围术期情况、实验室指标水平和术后随访情况。结果与对照组比较,观察组患者的手术切口小(P<0.05),术中出血量、术后引流量和术后镇痛药使用量少(P<0.05),住院时间短(P<0.05)。术前2组患者血清C反应蛋白(CRP)、白细胞介素(IL)-6、IL-8和肿瘤坏死因子(TNF)-α水平比较差异均无统计学意义(P>0.05);术后24、72 h,2组患者血清CRP、IL-6、IL-8和TNF-α水平均显著高于术前(P<0.05);2组患者术后72 h血清CRP、IL-6、IL-8和TNF-α水平均显著低于术后24 h(P<0.05);术后24、72 h,观察组患者血清CRP、IL-6、IL-8和TNF-α水平均显著低于对照组(P<0.05)。观察组患者术后并发症发生率和3 a复发率均显著低于对照组(P<0.05),观察组患者3 a存活率显著高于对照组(P<0.05)。结论 VATS治疗胸部肿瘤可减轻手术创伤,缩短住院时间,降低患者术后并发症发生率,提高患者存活率。
Objective To investigate the clinical effect of video assisted thoracoscopic surgery（VATS） in treatment of thoracic tumor. Methods Fifty-two patients with thoracic tumor were divided into two groups, twenty-six patients in control group were treated with traditional thoracotomy, while the twenty-six patients in observation group were treated with VATS. The peroperative situations, the level of laboratory parameters and postoperative follow-up were observed and compared between the two groups. Results Compared with control group, the size of operative incision was small （ P 〈 0.05 ）, the amount of bleeding in operation, the postoperative drainage and the dosage of postoperative analgesics were less （ P 〈 0.05 ） , and the hospitalization time was shorter in obervation group （P 〈 0.05 ）. Before operation, there was no significant differenee in the levels of serum C- reactive protein （CRP） , interleukin-6 （ IL-6 ） , IL-8 and tumor necrosis factor-a （ TNF-a ） between the two groups （ P 〈 0.05 ）. The levels of serum CRP, IL-6, IL-8 and TNF-a at the time of 24 and 72 hours after operation were significantly higher than those before operation in the two groups（ P 〈 0.05 ）. The levels of serum CRP, IL-6, IL-8 and TNF-o at the time of 72 hours af- ter operation were signifieantly lower than those at the time of 24 hours after operation in the two groups （ P 〈 0.05 ）. At the time of 24 and 72 hours after operation, the levels of serum CRP, IL-6, IL-8 and TNF-a in observation group were significantly lower than those in control group （P 〈 0.05 ）. The incidence of postoperative complications and 3-year recurrence rate in observa- tion group were significantly lower than those in control group（P 〈0.05 ）. The 3-year survival rate in observation group was sig- nifieantly higher than that in control group （ P 〈 0.05 ）. Conclusion VATS for the treatment of thoracic tumor can reduce surgi- cal trauma, shorten hospitalization time, reduce the incidence of postoperative complications, and improve survival rate of patients.
出处
《新乡医学院学报》
CAS
2013年第2期117-119,共3页
Journal of Xinxiang Medical University
关键词
电视胸腔镜手术
胸部肿瘤
开胸术
video assisted thoracoscopic surgery
thoracic tumor
thoraeotomy
