摘要
目的观察美洛西林用于剖宫产术前预防性感染治疗的效果。方法对71例剖宫产术前30～60min一次性应用美洛西林7g静脉滴注,并与同期的100例术后预防性应用美洛西林3.5g静脉滴注1日1次共5次的两组病例进行临床观察和研究分析对比。结果术前组在易感因素明显高于术后组的情况下,使术后病率从12%降至5.63%,切口感染率从7%降至1.41%,子宫内膜炎发生率从10%降至2.82%(P<0.05),有统计学意义;呼吸道感染及泌尿道感染均为P>0.05,无统计学意义,并且对新生儿无明显不利影响。结论足量美洛西林在剖宫产术前一次性应用可有效预防术后感染的发生率,对新生儿无影响,且用药时间短,抗生素用量少,无肠球菌、铜绿假单胞杆菌或念珠菌增殖现象,值得推广。
[ Objective ] To observe mezlocillin used for preoperative cesarean section preventive infection treatment effect. [ Methods ] 71 cases of preoperative cesarean section 30 - 60 minutes application mezlocillin 7 g intravenous drip, and compared with 100 cases of postoperative prophylactic use of mezlociUin 3.5 g intravenous drip a day once a total of 5 times of two groups of patients clinical observation and comparative analysis of the research. [ Resluts ] The preoperative group was significantly higher than susceptible factors of postoperative group, make the disease rate fell to 12% from 5.63%, incision infection rate from 7% to 1.41%, endometritis rate from 10% to 2.82%, P〈0.05, there is statistical significance; Respiratory infections and urinary tract infection are P 〉0.05, no statistical significance, and no obvious adverse effect to the newborn. [ Conclusion ] Mezlocillin sufficient preoperative cesarean section in disposable application can effectively prevent the incidence of postoperative infection of no effect, and use time is short, antibiotics usage, no enterococcus, pseudomonas aeruginosa and bacillus or monilial proliferation phenomenon, is worth popularizing.
出处
《中国妇幼卫生杂志》
2013年第1期18-19,共2页
Chinese Journal of Women and Children Health
关键词
美洛西林
剖宫产术
预防性应用
Mezlocillin
cesarean section
preventive application
