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心力衰竭患者血浆脑钠素及左室射血分数变化分析

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摘要 目的:观察充血性心力衰竭(CHF)患者血浆脑钠素水平(BNP)及左室射血分数(LVEF)与心功能分级之间的关系,探讨其临床意义。方法:75例CHF患者按NYHA分级分为4个亚组,采用放免法测定各组血浆BNP浓度,用超声心动仪(SONO1000)测定左室射血分数(LVEF)。结果:CHF患者血浆BNP浓度显著升高有统计学意义(P<0.01),且心功能越差升高越明显;血浆BNP浓度与LVEF之间具有良好的负相关(r=-0.59,P<0.01)。结论:CHF患者血浆BNP浓度随心力衰竭严重程度增加而升高,血浆BNP浓度能较好的评价CHF患者的心功能状态。
作者 谢咏梅 宝花 金花
机构地区 阿拉善盟中心医院康复医学科
出处 《内蒙古医学杂志》 2012年第11期1336-1337,共2页 Inner Mongolia Medical Journal
关键词 心力衰竭 血浆脑钠素 左室射血分数 心功能
分类号 R541.61 [医药卫生—心血管疾病]
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参考文献6

  • 1孟春,姚荣国,郭战利.脑型钠利尿肽与心力衰竭的诊断与治疗[J].疑难病杂志,2004,3(4):250-252. 被引量：3
  • 2Horio T, Shimada K, Kohno M, et al . Serial changes in atrial and brain natriuretic peptides in patients with acute myocardial infarc- tion treated with early coronary angioplasty [ J ]. Am Heart J, 1993, 126:293 - 299.
  • 3刘鹏,靳凤琳,张斌.慢性充血性心力衰竭患者血浆脑钠素、心钠素浓度与心功能的关系[J].泰山医学院学报,2006,27(5):414-415. 被引量：2
  • 4Schinkel AF, Vourvouri EC, BaxJ J, et al. Relation between left ventricular contractile reserve during low dosed obutamine echo cardiography and plasma concentrations of natriuretic peptides[ J ]. Heart, 2004, 90(3) :293 - 296.
  • 5Mir TS, Laux R, Hellwege HH, et al. Plasma concentrations of a minoterminal probrain natriuretic peptide in healthy neonates: marked and rapid increase after birth[J]. Pediatrics, 2003, 112 (4) :896 - 899.
  • 6Otario CE, Mifleman MA, Sutherland P, et al. Association be- tween increased estrogen status and increased fibrinolytic parential in the Framingham offspring study [ J]. Circulation, 1995, 41 (1):1 932-1 958.

二级参考文献30

  • 1[1]Hystad ME, Geiran OR, Attramadal H, et al. Regional cardiac expression and concentration of natriuretic peptides in patients with severe chronic heart failure. Acta Physiol Scand, 2001,171(4)395-403.
  • 2[2]McCullough PA. B-type natriuretic peptides. A diagnostic breakthrough in heart failure. Minerva Cardioangiol,2003,51 (2): 121-129.
  • 3[3]Magga J, Vuolteenaho O, Tokola H, et al. B-type natriuretic peptide: a myocyte-specific marker for characterizing load-induced alterations in cardiac gene expression. Am Med, 1998,30(Suppll): 39-45.
  • 4[4]Tremblay J, Desjardins R, Hum D, et al. Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases. Mol Cell Biochem,2002,203(1-2): 31-47.
  • 5[5]Chen HH,Bumett JC. The natriuretic peptides in heart failure:diagnostic and therapeutic potentials. Proc Assoc Am Physicians, 1999,111 (5): 406-416.
  • 6[6]Maisel, Padma K, Radmila K, et al. Utility of B-natriuretic peptide as a rapid, point-of-care test for screening patients undergoing echocardiography to determine left ventricular dysfunction. Am Heart J,2001,5:367-374.
  • 7[7]Tateishi J, Masutani M, Ohyanagi M, et al. Transient increase in plasma brain (B-type) natriuretic peptide after percutaneous transluminal coronary angioplasty. Clin Cardiol,2000,23(10) :776-780.
  • 8[8]Yamaguchi H, Yoshida J, Yamamoto K, et al. Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy. JACC, 2004,7: 43 ( 1 ): 55-60.
  • 9[9]Koglin J, Pehlivanli S, Schwaiblmair M, et al. Role of brain natriuretic peptide in risk stratification of patients with congestive heart failure. J Am Coll Cardiol,2001,38(7) :1934-1941.
  • 10[10]Lee SC, Stevens TL, Sandberg SM, et al. The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the outpatient treatment of heart failure. J Card Fail,2002,8(3):149-154.

共引文献3

内蒙古医学杂志
2012年 第11期

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