摘要
药物导致Q-T间期延长引发多形性室性心动过速或尖端扭转型室性心动过速(TdP),导致心室扑动或颤动比较罕见,但其为致命性心律失常,容易引起心源性猝死。本文介绍了容易引起Q-T间期延长的药物种类、作用机制与诱发Q-T间期延长的危险因素,以期加强对这些药物的认识,提供对此类药物的使用指导,促进合理安全用药。
Some Drugs can induce Q-T interphase prolongation, even torsades de pointes（TdP）. Though the side effect of drugs is no common, but is a fatal arrhythmia, and can cause sudden death. This paper introduces the drugs that can induce Q-T prolongation, their mechanism causing Q-T prolongation and some related risk factors, in order to strengthen the understanding of these drugs, provide guidance for the use of the drugs, and to promote rational and safe drug usage.
出处
《药品评价》
CAS
2012年第35期11-13,共3页
Drug Evaluation
