摘要
目的分析2009-2011年神经外科感染细菌分布及耐药性变化,为临床合理使用抗菌药物提供依据。方法回顾性分析2009-2011年神经外科感染细菌分布及耐药性,对其进行统计分析。结果 2009-2011年神经外科医院感染发生率分别为5.22%、4.69%及3.63%,明显高于全院同期的平均感染率;神经外科医院感染发生部位以颅内和下呼吸道最常见;2009年和2010年感染细菌以金黄色葡萄球菌为主,2011年以肺炎克雷伯菌为主;未检出葡萄球菌属对万古霉素、利奈唑胺的耐药菌株;肠杆菌科细菌对碳青霉烯类、加酶抑制剂较敏感;鲍氏不动杆菌对碳青霉烯类抗菌药物敏感性不高。结论坚持神经外科细菌耐药性监测,及时反馈给临床,对指导临床合理应用抗菌药物、积极控制感染具有重要意义。
OBJECTIVE To investigate the distribution of the bacteria causing infections in the neurosurgery department and analyze the change of antimicrobial resistance from 2009 to 2011 so as to provide basis for the reasonable clinical use of antibiotics. METHODS The distribution of the bacteria causing infections in the neurosurgery department from 2009 to 2011 as well as the drug resistance was retrospectively analyzed, and the statistical analysis was performed. RESULTS The incidence rates of nosocomial infections in the neurosurgery department during 2009- 2011 were 5. 22%, 4. 69%, and 3. 63%, respectively, significantly higher than the average infection rate in the same period. The intracranial infections and the lower respiratory tract infections were most common in the neurosurgery department; Staphylococcus aureus was the predominant species in 2009 and 2010, and Klebsiella pneurnoniae was dominant in 2011. No strains of vancomycin-resistant or linezolid-resistant Staphylococci were found; Enterobacteriaceae remained susceptible to carbapenems and enzyme-containing inhibitors ; Acinetobacter baumannii strains were not highly sensitive to carhapenems. CONCLUSION It is of great significance in guiding the reasonable use of antibiotics and in effectively controlling nosocomial infections to stick to the monitoring of bacterial resistance in neurosurgery department and to feedback to the hospital.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第6期1418-1419,共2页
Chinese Journal of Nosocomiology
关键词
神经外科
细菌
耐药性
抗菌药物
Neurosurgery department
Bacteria
Drug resistance
Antibiotics
