摘要
目的:观察异丙托溴铵联合沙丁胺醇及布地奈德雾化吸入治疗小儿毛细支气管炎的临床疗效。方法:将120例毛细支气管炎患儿随机分为治疗组62例和对照组58例,两组均给予对症支持治疗,治疗组在此基础上加用异丙托溴铵联合沙丁胺醇及布地奈德雾化吸入治疗,对照组加用沙丁胺醇及布地奈德雾化吸入治疗。观察两组患儿用药后症状缓解情况、肺部哮鸣音减少或消失时间及住院时间,比较两组疗效。结果:治疗后两组患儿临床症状及体征均有不同程度改善;治疗组在喘息、呼吸困难、肺部哮鸣音持续时间以及住院时间方面均短于对照组(P<0.05);治疗组总有效率98.39%,高于对照组的86.21%(P<0.05)。结论:异丙托溴铵联合沙丁胺醇及布地奈德雾化吸入治疗能提高小儿毛细支气管炎患儿的治愈率,缩短疗程。
Objective： To observe the therapeutic efficacy of inhaled ipratropium bromide combined with salbutamol and budesonide in the treatment of infant bronehiolitis. Methods： One hundred and twenty infants with bronchiolitis were divided into a treatment group （62 cases） and a control group （58 cases）. Both groups were treated with comprehensive and antiviral therapy. The treatment group was treated with inhaled ipratropium bromide combined with salbutamol and budesonide, and the control group was treated with inhaled salbutamol and budesonide. Clinical efficacy of both groups was evaluated. Results： After treatment the clinical symptoms and the signs of the two groups were improved in different degrees. In the treatment group, asthma, dyspnea relief time, the disappearing time of lung rale and length of hospital stay were shorter than those in the control group （P〈0.05）. The cure rate of the treatment group was 98.39%,while that of the control group was 86.21%. The clinical therapeutic efficacy was compared between the two groups, the differences had statistical significance. Conclusions： The result of the experiment indicates that the therapeutic efficacy of inhaled ipratropium bromide combined with salbutamol and budesonide in the treatment of infant bronchiolitis is satisfactory.
出处
《儿科药学杂志》
CAS
2013年第3期12-14,共3页
Journal of Pediatric Pharmacy
