摘要
目的:探讨小剂量他达拉非降阶梯治疗对心因性勃起功能障碍的疗效。方法:采用勃起功能国际指数问卷(IIEF-5)、勃起硬度分级评分(EHS)。将门诊诊断为心因性勃起功能障碍共84例患者随机分小剂量他达拉非降阶梯治疗组(观察组,n=42)、按需治疗组(对照组,n=42)治疗2个月,进行治疗前后及组间对比评分。结果:对照组5例失访共79例完成观察研究。两组治疗后IIEF-5评分、EHS较治疗前均明显提高。观察组、对照组治疗ED有效率分别达95.2%、86.5%,与对照组相比,观察组有更高的有效率以及依从性(P<0.05)。结论:他达拉非对心因性勃起功能障碍具有良好作用,小剂量他达拉非降阶梯治疗优于按需治疗。
Objective： To investigate the effect of low-dose daily de-escalatory administration of tadalafil on psychological erectile dysfunction （ED）. Methods ： We randomized 84 psychological ED patients into an observation and a control group of equal num- ber to receive low-dose daily de-escalatory administration and on-demand medication of tadalafil, respectively, both for 2 months. We compared the scores on IIEF-5 and erection hardness （EHS） between the two groups before and after the treatment. Results： The treatment and follow-up were accomplished for 79 cases, with 5 withdrawals in the control group. The IIEF-5 and EHS scores were remarkably improved in both the observation and control groups after treatment. The rate of therapeutic effectiveness was significantly higher in the observation group than in the control （95.2% vs 86.5%, P 〈 0.05）. Conclusion ： Low-dose daily de-escalatory administration of tadalafil is highly effective and even better than on-demand medication of tadalafil for psychological ED.
出处
《中华男科学杂志》
CAS
CSCD
2013年第3期241-246,共6页
National Journal of Andrology
关键词
勃起功能障碍
他达拉非
小剂量
心因性
降阶梯治疗
erectile dysfunction
tadalafil
low-dose
daily administration
psychological
de-escalatory administration
