期刊文献+

宫腔内人工授精手术操作对周期妊娠率的影响 被引量:4

Effects of operation factors on the outcomes of intrauterine insemination
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摘要 目的:探讨宫腔内人工授精周期影响妊娠率的手术操作因素。方法:回顾性分析1359个人工授精周期,分析手术操作中宫颈黏液清除、宫腔出血、精液漏出等因素对周期妊娠率的影响。结果:术中清除宫颈黏液434个周期,妊娠率13.14%,未清除者925个周期,周期妊娠率11.46%,两组妊娠率差异无显著性。术中宫腔出血周期299个,妊娠者37个,无出血周期1060个,妊娠者126个,两组临床妊娠率无差异(12.37%,11.89%,P>0.05)。术中存在精液漏出周期450个,妊娠者41个,无漏出周期909个,妊娠者122个,存在精液漏出周期临床率显著低于无漏出周期(9.11%13.42%,P<0.05)。结论:人工周期手术操作中宫颈黏液清除、宫腔出血对周期妊娠率无明显影响,精液漏出显著降低周期妊娠率。 Objective To evaluate the effects of operation factors on the outcomes of intrauterine insemination (IUI). Methods 1 359 IUI cycles from Jan 2006 to Jul 2012 were included. Effects of the operation factors including clearance of cervical mucus, uterus bleeding and sperm leaking on clinical pregnancy rates (PRs) were analyzed. Results PRs of 434 cycles with and of 925 cycles without clearance of cervical mucus were 13.14% and 11.46% (P 〉 0.05) ; those of 299 cycles with and of 1060 cycles without uterus bleeding were 12.37% and 11.89% (P 〉 0.05); and those of 450 cycles with and 909 cycles without sperm leaking were 9.11% and 13.42% (P 〈 0.05). Conclusions The process of cervical mucus cleaning and uterus bleeding in operation had no effects on the outcomes of IUI. Sperm leaking in operation could evidently reduce the PRs of IUI.
出处 《实用医学杂志》 CAS 北大核心 2013年第6期959-961,共3页 The Journal of Practical Medicine
关键词 人工授精 手术 妊娠率 Intrauterine insemination Operation Pregnant rates
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参考文献10

  • 1Haagen E C, Hennens R P, Nelen W L, et al. Subfertility guidelines in Europe: the quantity and quality of intrauterine insemination guidelines [J]. Hum Reprod, 2006,21 (8): 2103-2109.
  • 2陈益鲁,侯晓红,黄朝霞.来曲唑促排卵在多囊卵巢综合征患者宫腔内人工授精中的应用[J].实用医学杂志,2011,27(5):861-863. 被引量:10
  • 3Haagen E C, Nelen W L, Grol R P, et al. Variation in guideline adherence in intrauterine insemination care [J]. Reprod Biomed Online, 2010, 20(4):533-542.
  • 4李雪梅,朱文杰,周永红,付志红,陈秀敏,谭真.密度梯度离心法分离精子在宫腔内人工授精中的应用[J].实用医学杂志,2009,25(14):2288-2290. 被引量:11
  • 5付志红,朱文杰,陈秀敏,李雪梅,谭真,周永红.超排卵对宫腔内人工授精周期妊娠率的影响[J].中国妇产科临床杂志,2008,9(5):332-335. 被引量:5
  • 6Porter M B. Ultrasound in assisted reproductive technology [J]. Semin Reprod Med, 2008,26 (3) : 266-276.
  • 7Mansour R. Minimizing embryo expulsion after embryo transfer: a randomized controlled study [J]. Hum Reprod, 2005,20( 1 ) : 170-174.
  • 8Koutsougeras G, Vakalopoulos I, Nikolettos N, et al. The effects of benzoylecgonine, oxytocin, ritodrine and atosiban on the contractility of myometrium. An experimental study [J]. Clin Exp Obstet Gynecol, 2012,39( 1 ) : 36-42.
  • 9Pierzynski P. Oxytoein and vasopressin V (1A) receptors as new therapeutic targets in assisted reproduction [J]. Reprod Biomed Online, 2011,22 ( 1 ) : 9-16.
  • 10Kido A, Togashi K, Hatayama H, et al. Uterine peristalsis in women with repeated IVF failures: possible therapeutic effect of hyoscine bromide [J]. J Obstet Gynaecol Can, 2009,31 (8) : 732-735.

二级参考文献28

  • 1郁琦,邓成艳,何方方.子宫内膜异位症不孕的诱导排卵治疗[J].实用妇产科杂志,2007,23(3):135-137. 被引量:8
  • 2章汉旺,李莉,李清,邓彧,段秀娟.来曲唑和克罗米酚对小鼠着床期子宫内膜容受性的影响[J].生殖与避孕,2007,27(4):251-254. 被引量:27
  • 3谷翊群,陈振文,于和鸣,等,世界卫生组织编.WHO人类精液及精子-宫颈粘液相互作用实验室检验手册[M].4版.北京:人民卫生出版社,2001:5-64.
  • 4Henkel R R,Schill W B.sperm preparation for ART[J].Reprodu Biol Endocrinol,2003,1:108.
  • 5Ding D C,Huang Y C,Liu J Y,et al.Comparison of nitric oxide production and motion characteristics after 3-layer percoll and LxaPrep preparation methods of human sperm[J].Arch Gynecol Obstet,2002,266(4):210-213.
  • 6Rosselli M,Dubey R K,Imthurn B,et al.Effects of nitric oxide on human spermatozoa:evidence that nitric oxide decreases sperm motility and induces toxicity[J].Hum Reprod,1995,10(7):1786-1790.
  • 7Soderlund B,Lundin K.The use of silane-coated silica particles for density gradient centrifugation in in vitro fertilization[J].Hum Reprod,2000,15(4):857-860.
  • 8Chen M J,Bongso A.comparative evaluation of two density gradient preparations for sperm separation for medically assisted conception[J].Hum Reprod,1999,14(3):759-764.
  • 9[1]Farhi J,Haroush AV,Lande Y,et al.Role of treatment with ovarian stimulation and intrauterine insemination in women with unilateral tubal occlusion diagnosed by hysterosalpingography.Fertil Steril,2007,88:396-400.
  • 10[2]Steures P,Steeg JW,Hompes PG,et al.The additional value of ovarian hyperstimulation in intrauterine insemination for couples with an abnormal postcoital test and a poor prognosis:a randomized clinical trial.Fertil Steril,2007,88:1618-1624.

共引文献22

同被引文献39

  • 1赵芳,孙莹璞,苏迎春,郭艺红.影响宫腔内人工授精临床妊娠率的相关因素分析[J].生殖与避孕,2009,29(1):21-25. 被引量:47
  • 2胡京美,颜军昊,李媛,陈子江.混匀上游法人工授精治疗抗精子抗体阳性不孕症患者的效果[J].重庆医学,2005,34(10):1522-1524. 被引量:4
  • 3林虹,张炜,李志凌,肖婉芬,王玉莲.宫腔内人工授精治疗免疫性不孕的效果[J].中国临床医学,2005,12(6):1071-1072. 被引量:5
  • 4Ombelet W, Dhont N, Thijssen A, et al. Semen quality and prediction of IUI success in male subfertility: a systematic review [ J ]. Reprod Biomed Online, 20 lg, 28 (3) : 300-309.
  • 5Marshbum PB, Alanis M, Matthews ML, et al. A short period of ejaculatory abstinence before intrauterine insemination is associated with higher pregnancy rates [J]. Fertil Steril, 2010, 93(1) :286-288.
  • 6Van den Boogaard E, Vissenberg R, Land JA,et ;1. Significanceof (sub)clinical thyroid dysfunction and thyroid autoimmunitybefore conception and in early pregnancy : a systematic review [J].Hum Reprod Update, 2011,17(5) :605-619.
  • 7Mansourian AR. Female reproduction physio ogy adverselymanipulated by thyroid disorders: a review of liteiature [J]. PakJ Biol Sci, 2013,16(3):112-120.
  • 8Grassi G, Balsamo A, Ansaldi C, et al. Thyroic autoimmunityand infertility [J]. Gynecol Endocrinol, 2001,15(5) :389-396.
  • 9Bellver J, Soares SR, Alvarez C, et al. TTie role o' thrombophiliaand thyroid autoimmunity in unexplained infertility,implantationfailure and recurrent spontaneous abortion [J]. Hum Reprod.2008,23(2):278-284.
  • 10Tan S, Dieterle S, Pechlivanis S, et al. Thyroid autoantibodiesper se do not impair intracytoplasmic sperm injecl ion outcome ineuthyroid healthy women [J]. Eur J Endocrinol, 1014,170(4):495-500.

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