摘要
目的探讨肝脏原发性神经内分泌癌的临床病理特点及诊断治疗。方法综合国内文献报告的47例位于肝脏的原发性神经内分泌癌患者的症状、影像、病理、治疗及随访情况,结合文献进行分析。结果术前无特异临床症状,均为查体发现。术前容易通过影像学检查发现但难以确诊。最终诊断依靠病理学表现和免疫组化。文献报道的肝脏原发性神经内分泌癌非常罕见。结论肝脏原发性神经内分泌癌是一种非常罕见的肝脏恶性肿瘤,多为低度恶性肿瘤,依靠病理学方法确诊,根治性切除是治疗的首选。建议术后长期随访。
Objective To discuss the clinical pathologic features of primary hepatic neuroen-docrine carcinoma. Methods The clinic, imaging, pathology features and treatment of 47 patients were analyzed retrospectively and related literatures were reviewed. Results The patient had not special symptoms and signs. The imaging methods can easily find the tumor but hard to differentiate it, The final diagnosis depends on the pathologic features and immunohistochemistry technipue.Among present litertures ,scarce cases of primary hepatic neuroendocrine carcinoma were reported. Conclusion Primary hepatic neuroendocrine carcinoma is an extremely rare tumor of the liver. The diagnosis of primary hepatic neuroendocrine carcinoma mainly depends on the pathological features. Resection is the first choice of treatment for primary hepatic neuroendocrine carcinoma and provides the most favorable outcomes including longterm survival. It should be followed up for a long term.
出处
《中国现代医生》
2013年第4期61-63,共3页
China Modern Doctor
关键词
肝脏肿瘤
神经内分泌癌
肝内转移
免疫组织化学
Livertum
Neuroendocrine carcinoma
Intrahepatic metastasis
Immunhistochemistry
