摘要
目的:探讨阿托伐他汀早期强化疗法在急性心肌梗死(AMI)介入治疗术后(PCI)患者中的临床应用价值。方法:将106例行PCI治疗的AMI患者随机分为观察组和对照组各53例,观察组采用大剂量阿托伐他汀强化治疗,对照组采用常规剂量治疗。结果:治疗后两组TC及LDL-C水平均有明显下降,与治疗前比较有显著性差异(P<0.05),观察组下降更为明显,组间比较有显著性差异(P<0.05);观察组共发生主要不良心血管事件4例,对照组共发生7例,两组比较有显著性差异(P<0.05)。结论:对PCI术后的AMI患者采用早期强化治疗剂量的阿托伐他汀,能显著改善患者的血脂水平,降低主要不良心血管事件的发生率,值得临床推广。
Objective：Effects of atorvastatin on early intensive therapy in acute myocardial infarction（AMI） after interventional therapy（PCI） patients in clinical application.Methods：106 cases of PCI treated by AMI were randomly divided into the observation group and the control group with 53 cases in each group,the observation group was treated with high dose atorvastatin treatment,the control group using conventional dose therapy.Results：After treatment in the two groups TC and LDL-C levels were significantly decreased compared with those before treatment,there were significant differences（P0.05）,the observation group decreased more significantly,compared between groups with significant difference（P0.05）;the observation group were major adverse cardiovascular events in 4 cases,control group with 7 cases,two groups have significant differences（P0.05）.Conclusion：On PCI patients with AMI after treatment with early intensive atorvastatin,can significantly improve the patient＇s lipid levels,reduced major adverse cardiovascular event rates,worthy of clinical application.
出处
《中国医药导刊》
2013年第2期311-311,313,共2页
Chinese Journal of Medicinal Guide
关键词
阿托伐他汀
急性心肌梗死
介入治疗
Atorvastatin
Acute myocardial infarction
Interventional therapy
