摘要
目的:对比硼替佐米联合地塞米松(BD)方案和沙利度胺联合地塞米松(TD)方案对老年多发性骨髓瘤患者的疗效及不良反应。方法:回顾性分析24例老年多发性骨髓瘤病例,随机分为BD组和TD组,统计分析2组的缓解率及生存时间。结果:4个疗程后,BD组完全缓解(CR)4例,部分缓解(PR)6例,TD组完全缓解2例,部分缓解4例。BD组2年存活9例,4年存活5例,TD组2年存活6例,4年存活3例。BD组缓解率,生存期优于TD组。结论:BD方案较TD方案更适于老年多发性骨髓瘤患者的化疗。
Objective：To compare the curative effect and side-effects of BD regimen in old multiple myeloma（MM） patients with TD regimen. Method：Data from 24 old multiple myeloma patients wer retrospectively analyzed who were divided into BD group and TD group.The remission rate and survival time were compared between two groups. Result：After four courses of treatment,four cases acquired CR and six cases acquired PR in BD regimengroup while in TD regimen group,two cases got CR and four cases got PR.2-years after treatment,nine cases survived in BD group and six survived in TD group.4 years after treatmen,five cases survived in BD group and three survived in TD group.The remission rate and survival time in BD groupare better than those in TD group. Conclusion：BD regimen is more suitable than TD regimen for old multiple myeloma patients.
出处
《临床血液学杂志》
CAS
2013年第2期190-192,共3页
Journal of Clinical Hematology
