摘要
目的探讨恙虫病的临床特点,为早期诊断与治疗提供依据。方法回顾性分析84例恙虫病住院患者的临床资料,分析治愈患者与危重患者的临床特征。结果患者均有畏寒、发热、乏力、头痛及全身酸痛症状,80例出现特异性焦痂。84例中有16例危重患者,其中8例死亡。与治愈患者相比,危重患者出现尿蛋白/尿红细胞(100%),肝肾功能严重受损(TBIL>85.5μmol/L者占60%;CRE>200μmol/L者占80%)、中枢神经系统受损(60%)及凝血功能受损(PTA<40%者占80%)明显增多。结论恙虫病临床表现多样。危重患者有多器官损害,如肝肾功能、凝血功能严重受累及中枢神经系统损害(出现神志障碍等),上述情况或是病情危重的信号。
Objective To investigate the clinical features of tsutsugamushi disease in order to provide evidence for the diagnosis and treatment of the disease. Methods Clinical data of 84 hospitalized patients diagnosed with tsutsugamushi disease in our hospital were analyzed retrospectively, and the clinical characteristics of the clinically cured patients and critically ill patients were summarized as well. Results All patients had the symptoms of fear of cold, fever, fatigue, headache and pains all ow^r. Eighty pa- tients had specific eschar. Of 84 patients, 16 were critically ill patients, of whom 8 died. Compared with elinically cured patients, critically ill patients showed urine protein or hematuresis （100%）, liver and kidney serious injure （60% patients of TBII, more than 85.5μmol/L and 80% patients of CRE more than 200 μmol/L）, central nervous system injury （60%） and coagulation disorders （80% patients of PTA less than 40%）. Conclusions Clinical manifestations of tsutsugamushi disease are diverse and complieated with a high rate of misdiagnosis. Critically ill patients are affected with multiple organ injury, such as liver and kidney serious injure, coagu- lation disorders and central nervous system injury （e.g. conscious disturbance）, which are the risk factors of critical condition in patients with tsutsugamushi disease.
出处
《传染病信息》
2013年第1期50-52,共3页
Infectious Disease Information
