期刊文献+

血清C反应蛋白对不稳定型心绞痛患者预后考核的价值 被引量:1

Value of serum CRP in prognostic assessment of patients with unstable angina
下载PDF
导出
摘要 目的观察探讨检测血清C反应蛋白(CRP)水平对评估不稳定型心绞痛患者预后的临床应用价值。方法选取该院2009年1月至2011年1月不稳定型心绞痛患者92例,皆在入院后接受常规内科治疗,根据入院后检测血清CRP水平分为A组(血清CRP高水平)52例和B组(血清CRP低水平)40例,观察对比两组患者入院后2周和随访6个月的心绞痛发作次数、远期心血管事件发生率。结果 A组患者入院后2周和随访6个月的心绞痛发作次数分别为(4.9±0.6)次和(13.7±1.4)次,明显高于B组患者,比较差异有统计学意义(P<0.05);A组入院后2周和随访6个月AMI发生率分别为30.8%和23.1%,明显高于B组,比较差异有统计学意义(P<0.05);A组入院后2周和随访6个月猝死率与B组比较差异无统计学意义(P>0.05)。结论检测血清CRP水平对评估不稳定型心绞痛患者预后有重要的临床应用价值。 Objective To investigate the clinical value of serum CRP levels to assess the prognosis of patients with unstable angina. Methods In our hospital from January 2009 to January 2011,92 cases of unstable angina pa- tients were given conventional medical treatment after admission, and they were divided into group A (serum CRP high level, n= 52) and group ]3 (serum CRP low level, n= 40). The number of angina attacks and long-term cardio- vascular event rates of the patients were observed after two weeks and followed up for six months. Results The number of angina attacks of group A was significantly higher than that of group B patients, and the difference was significant (P〈0.05). AMI incidence in group A was higher than that in group B,and the difference was significant (P〈0.05). The death rate compared with group B was not significantly different (P^0.05). Conclusion The serum CRP level has important clinical value in prognosis assessment of patients with unstable angina.
作者 王琼
出处 《检验医学与临床》 CAS 2013年第7期824-825,共2页 Laboratory Medicine and Clinic
关键词 血清C反应蛋白 不稳定型心绞痛 心血管事件 预后 serum CRP unstable angina cardiovascular events prognosis
  • 相关文献

参考文献12

二级参考文献60

  • 1姜仲辉,葛美玉,王华.2002—2006年我院收治冠心病现状分析[J].中国医院统计,2008,15(4). 被引量:2
  • 2潘清蓉,孙梅励.C-反应蛋白在动脉粥样硬化中的作用[J].基础医学与临床,2004,24(4):462-465. 被引量:29
  • 3葛智平,陈晓春.C反应蛋白与不同类型冠心病相关性的临床研究[J].临床心血管病杂志,2005,21(2):78-80. 被引量:37
  • 4刘颖,李永杰,高旭光.急性脑梗死患者血浆同型半胱氨酸水平及其相关因素分析[J].中国全科医学,2006,9(19):1611-1613. 被引量:35
  • 5Pradhan AD, Manson JE, Rifai N, et al. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus [ J ]. JAMA, 2001,286(3) :327-334.
  • 6Retnakaran R, Hanley A J, Raif N, et al. C-reactive protein and gestational diabetes: the central role of maternal obesity[J]. Clin Endocrinol Metab, 2003,88 ( 8 ) :3507-3512.
  • 7Pickup JC, Mattock MB, Chusney GD, et al. NIDDM as a disease of the innate immune system: association of acute-phase reactants and intedeukin-6 with metabolic syndrome X [J].Diabetologia, 1997,40 ( 11 ) : 1286-1292.
  • 8Kado S, Nagase T, Nagata N, et al. Circulating levels of interleu-kin-6, its soluble receptor and interleukin-6/interleukin-6 receptor complexes in patients with type 2 diabetes mellitus[ J]. Aeta Diabetol, 1999,36(1-2) :67-72.
  • 9Devaraj S, Jialal I. Alpha tocopherol supplementation decreases sex-um C-reactive protein and monocyte interleukin-6 levels in normal volunteers and type 2 diabetic patients [ J ]. Free Radie Biol Med,2000,29 (8) :790-792.
  • 10Ross R.Atherosclerosis-an inflammatory disease[J].N Engl J Med,1999,340(2):115.

共引文献117

同被引文献9

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部