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抗甲状腺抗体与妊娠相关疾病关系的研究进展 被引量：43

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摘要 抗甲状腺抗体（antithyroid antibody，ATA）包括抗甲状腺过氧化物酶抗体（thyroid peroxidase antibody，TPOAb）和甲状腺球蛋白抗体（thyroglobulin antibody，TgAb）。在自身免疫性甲状腺疾病中如桥本甲状腺炎、约67％的产后甲状腺炎、75％的毒性弥漫性甲状腺肿患者血清中均能检测mATA。ATA被认为能通过抗体、补体介导的细胞毒性作用，损伤甲状腺细胞，引起甲状腺功能低下，进而对妇女健康产生不良影响。在育龄期妇女中，甲状腺功能低下和月经异常之间存在关联，严重的甲状腺功能低下甚至可导致卵巢功能障碍，从而导致不孕。
作者 江琳琳 黄佳 杨冬梓
机构地区 中山大学孙逸仙纪念医院生殖中心
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2013年第3期222-224,共3页 Chinese Journal of Obstetrics and Gynecology
关键词 抗甲状腺抗体 妊娠相关疾病 抗甲状腺过氧化物酶抗体 甲状腺功能低下 自身免疫性甲状腺疾病 毒性弥漫性甲状腺肿 甲状腺球蛋白抗体 桥本甲状腺炎
分类号 R714.25 [医药卫生—妇产科学]
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参考文献29

  • 1Stagnaro-Green A, Chen X, Bogden JD, et al. The thyroid and pregnancy:a novel risk factor for very preterm delivery. Thyroid, 2005,15:351-357.
  • 2Casey BM, Dashe JS, Wells CE,et al. Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol,2005 ,105 :239-245.
  • 3Kim CH, Chae HD, Kang BM, et al. Influence of antithyroid antibodies in euthyroid women on in vitro fertilization-embryo transfer outcome. Am J Reprod hnmunol, 1998,40:2-8.
  • 4Poppe K, Glinoer D, Tournaye H, et al. Assisted reproducti and thyroid autoimmunity: an unfortunate combination?. J CI| I Endocrinol Metab,2003,88:41494152. /.
  • 5Revelli A, Casano S, Plane LD, et al. A retrospective study on 1VF outcome in euthyroid patients with anti-thyroid antibodies: eftcts of levothyroxine, acetyl-salicylic acid and prednisolone adjuvant treatments. Reprod Biol Endocrinol,2009 ,7 :137.
  • 6Kutteh WH, Yetnmn DL, Can AC,et al. Increased prevalence of antithyroid antibodies identified in women with recurrent pregnancy loss but not in women undergoing assisted reproduction. Fertil Steril, 1999,71:843-848.
  • 7Janssen OE, Mehhnauer N, Hahn S, et al. High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Eur J Endocrino1,2004 ,150 :363-369.
  • 8Mecacci F, PmTetti E, Cioni R,et al. Thyroid autoimmunity and its association with non-organ-specific antibodies and subclinical alterations of thyroid function in women with a history of pregnancy loss or preeclampsia. J Reprod Immunol,2000,46:39-50.
  • 9Dendrinos S, Papasteriades C, Tarassi K, et al. Thyroid autoimmunity in patients with recurrent spontaneous miscarriages. Gynecol Endocrino1,2000 ,14 :270-274.
  • 10高金瑜,王谢桐.甲状腺自身抗体与复发性流产关系的初步探讨[J].中国实用妇科与产科杂志,2006,22(12):915-917. 被引量：22

二级参考文献13

  • 1张新宇,刘善芬,门新华,申安媛.抗核抗体与妊娠[J].中国妇产科临床杂志,2001,2(6):379-384. 被引量：3
  • 2林其德,肖云山.抗磷脂综合征与病理妊娠[J].中国实用妇科与产科杂志,2004,20(5):264-266. 被引量：42
  • 3Kutteh WH,Yetman DL,Carr AC,et al.Increased prevalence of antithyroid antibodies identified in women with recurrent pregnancy loss but not in women undergoing assisted reproduction[J].Fertil Steril,1999,71 (5):843-848.
  • 4Ellen M,Joseph AH,Susan JM.Thyroiditis after pregnancy[J].J Clin Endocrinol Metab,1997,82 (8):2455-2457.
  • 5Mecacci F,Parretti E,Cioni R,et al.Thyroid autoimmunity and its association with non-organ-specific antibodies and subclinical alterations of thyroid function in women with a history of pregnancy loss or preeclampsia[J].J Reprod Immunol,2000,46(1):39-50.
  • 6Stricker RB,Steinleltner A,Bookoff CN,et al.Successful treatment of immunologic abortion with low-dose intravenous immunoglobulin[J].Fertil steril,2000,73 (3):536-540.
  • 7Sheth JJ,Sheth FJ.Study of anticardiolipin antibodies in repeated abortions an institutional experince[J].Indian J Pathol Microbiol,2001,44(2):117-121.
  • 8Rodien P,Coutant R,Vasseur C,et al.Thyroid dysfunction and pregnancy[J].Rev Prat,2005,55 (2):174-179.
  • 9Poppe K,Glinoer D,Touraaye H,et al.Assisted reproduction and thyroid autoimmunity:an unfortunate combination?[J].J Clin Endocrinol Metab,2003,88(9):4149-4152.
  • 10Matalon ST,Blank M,Levy Y,et al.The pathogenic role of anti-thyroglobulin antibody on pregnancy:evidence from an active immunization model in mice[J].Hum Reprod,2003,18 (5):1094-1099.

共引文献21

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引证文献43

二级引证文献299

中华妇产科杂志
2013年 第3期

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