摘要
目的:探讨放疗配合化疗应用于恶性胶质瘤术后治疗的临床效果。方法:入选2009年2月-2012年11月在本院进行住院治疗的恶性胶质瘤患者79例,根据患者在住院期间选择治疗方式的不同,将所有患者分为对照组(单纯采用化疗治疗,n=37)和观察组(采用化疗联合放疗治疗,n=42),比较两组患者临床效果。结果:观察组无进展生存时间、平均总生存时间分别为(10.9±6.27)周、(57.32±8.36)周均显著高于对照组(4.78±1.42)周、(44.79±5.72)周,差异均具有统计学意义(P<0.05);观察组随访结束时生存率为14.3%显著高于对照组5.4%,差异具有统计学意义(P<0.05);两组患者在治疗过程中均未出现严重的不良反应。结论:在放疗的基础上采用化疗治疗,临床效果显著,能显著改善患者生活质量,改善预后。
@@@@Objective:To study radiotherapy in combination with chemotherapy used in the treatment of malignant glioma clinical effect. Method:In February 2009 to November 2012,79 cases of patients with malignant glioma in our hospital were collected. According to patients in hospital in the choice of different treatment,all patients were divided into control group(simple chemotherapy treatment,n=37)and the observation group(chemotherapy combined radiation therapy,n=42),and compared two groups of patients clinical effect. Result:Observed groups were progression-free survival time, average total survival time were(10.9±6.27),(57.32±8.36)weeks,which were significantly higher than those in the control group patients(4.78±1.42), (44.79±5.72)weeks(P<0.05);At the end of the study,observation group patients were followed up for a 5-year survival rate was 14.3%,which wassignificantly higher than those in the control group patients 5.4%and the difference was statistically significant(P<0.05). Two groups of patients in the treatment process all did not appear serious adverse reactions. Conclusion:On the basis of radiotherapy in chemotherapy treatment,the clinical effect is remarkable and the patients can improve the quality of life and improve the prognosis as well.
出处
《中国医学创新》
CAS
2013年第9期30-31,共2页
Medical Innovation of China
关键词
放疗
化疗
恶性胶质瘤
临床效果
Chemotherapy
Radiotherapy
Malignant glioma
Clinical effect
