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过敏性鼻炎-哮喘综合征治疗方法的成本效果分析 被引量:4

The Cost-effectiveness analysis of the treatment of allergic rhinitis-asthma syndrome
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摘要 目的:探讨过敏性鼻炎-哮喘综合征治疗方法的成本效果,从而选择合理的治疗药物。方法:过敏性鼻炎-哮喘综合征患者200例根据药物应用的不同分为糖皮质激素组(A组)、抗组胺组(B组)、白三烯受体拮抗剂组(C组)、抗-IgE单克隆抗体组(D组)和转移因子组(E组),分别应用相应的药物治疗。结果:D组与E组的有效率都高于A组、B组、C组(P<0.05),D组与E组的成本明显高于A组、B组、C组(P<0.05),A组与C组的C/E值明显少于其他三组(P<0.05),进行敏感度分析,表明影响因素在一定的变化范围内并不影响结果。结论:糖皮质激素法与白三烯受体拮抗剂法是治疗过敏性鼻炎-哮喘综合征的最佳治疗方法,值得推广应用。 Objective To investigate the cost-effectiveness of allergic rhinitis-asthma syndrome treatment for reasonable choice of treatment drugs.Methods 200 cases of allergic rhinitis-asthma syndrome patients were equally divided into glucocorticoid group(A),the anti histamine group(B),leukotriene receptor antagonist group(C group),anti-IgE monoclonal antibody group(D) and transfer factor group(E) depending on the drug application respectively,there were appled the appropriate medication.Results Group D and E efficiency were higher than A,B,C group(P 0.05),D group and E group cost were significantly higher than the A,B,C group(P〈0.05),group A and group C C/E values significantly were less than the other three groups(P〈0.05),sensitivity analysis showed that the influencing factors can not affect the results.Conclusion The glucocorticoid law and leukotriene receptor antagonists are the best treatment for the treatment of allergic rhinitis-asthma syndrome,should be widely applied.
出处 《吉林医学》 CAS 2013年第9期1619-1620,共2页 Jilin Medical Journal
关键词 过敏性鼻炎-哮喘综合征 成本效果 糖皮质激素 白三烯受体拮抗剂 Allergic rhinitis-asthma syndrome Cost-effectiveness Glucocorticoids Leukotriene receptor antagonists
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  • 1向莉,申昆玲,张亚梅,贺建新,张杰,任亦欣,李珍.3~14岁哮喘和变应性鼻炎患儿吸入性致敏原分布特征比较[J].中国实用儿科杂志,2006,21(8):581-583. 被引量:26
  • 2王秋萍,薛飞,李泽卿,郑璐.过敏性鼻炎和支气管哮喘治疗的统一性与整体观[J].医学与哲学(B),2006,27(10):51-52. 被引量:9
  • 3Bousquet J , Van Cauwenberge P , Khaktaev N. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol , 2001,108 : s147 - 334.
  • 4Corren J , Adinoff AD , Irvin CG. Changes in bronchial responsive- ness fallowing nasal provocation with allergen. J Allergy C/in Immu- no1,1992,89:611-618.
  • 5Fuhlbrigge A L , Adams R J. The effect of treatment of allergic rhinitis on asthma morbidity, including emergency department visits. Curr Opin Allergy C|in Immunol,2003,3 (1) :29 -32.
  • 6Fujimoto K,Kubo K,Yamamoto H,et al.Eosinophilic inflammation in the airway is related to glucocorticoid reversibility in patients with pulmonary emphysema[J].Chest,1999,115(3):697-702.
  • 7Nie HX, Yang J, Hu SP, et al. Effects of theophylline on CD4+ lymphocyte, interleukin-5, and interferon gamma in induced sputum of asthmatic subjects[J].Atca Pharmacol Sin,2002,23(3):267-272.
  • 8Pauwels RA,Buist AS,Calverley PM,et al.Global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease:NHLBI/WHO Global Initiative for Chronic Obstructive Pulmonary Disease (GLOD) workship summary[J].Am J Respir Crit Care Med,2001,163(5):1256-1276.
  • 9Stanescu D, Fournier M, Lebargy F, et al. Airway obstruction, chronic expectoration and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils[J].Thoax,1996,51(3):267-273.
  • 10British Thoracic Society.The British guidelines on asthma management[J].Thorax,1997,52 (Suppl 1):1-21.

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