摘要
目的探讨纳洛酮与醒脑静联合抢救慢性阻塞性肺部疾病(COPD)并Ⅱ型呼吸衰竭的临床效果。方法将256例COPD并Ⅱ型呼吸衰竭患者随机分为治疗组与对照组。治疗组128例采用纳洛酮联合醒脑静治疗,对照组128例用常规方法治疗。结果治疗组总有效率(98.44%),对照组总有效率为95.31%,两组比较差异无统计学意义;而治疗组显效率为88.28%,明显高于对照组52.34%,差异有统计学意义;血气分析:两组比较差异无统计学意义;动脉血气分析指标:动脉血氧分压(PaO2)明显高于对照组(P<0.05),差异有统计学意义;动脉血二氧化碳分压(PaCO2)稍低于对照组(P>0.05),差异无统计学意义。结论纳洛酮与醒脑静联合治疗性阻塞性肺气肿并Ⅱ型呼吸衰竭临床疗效确切。
Objective To investigate the effectiveness of naloxone with Xingnaojing joint rescue chronic obstructive pulmonary disease （COPD） and type Ⅱ respiratory failure clinical observation. Methods A total of 256 patients with COPD and type Ⅱ respiratory failure were randomly divided into two groups： the treatment group and the control group. 128 cases in the treatment group, be treated by naloxone with Xingnaojing of treatment, 128 cases in control group be treated by traditional methods. Results The overall effective rate for treatment group was 98.44%, and the overall ef- fective rate of the control group is 95.31%. There were not significant differences on overall effectiveness between the two groups. While the dominant effective rate for treatment group is 88.28%, that of the control group was 52.34%, the dominant effectiveness for treatment group was significantly higher than the control group＇s. Blood gas analysis indicat- ed the treatment group and the control group showed no significant differences. The arterial blood gas analysis indicat- ed the arterial partial pressure of oxygen （PaO2） was significantly higher than that in the control group＇s （P 〈 0.05）, ar- terial partial pressure of carbon dioxide （PaCO2） slightly lower than the control group （P 〉 0.05） and there is not sig- nificant differences on PaCO2. Conclusion Naloxone and Xingnaojing combination therapy for obstructive emphysema and respiratory failure type Ⅱ clinical has confirmed efficacy.
出处
《中国现代医生》
2013年第7期130-132,共3页
China Modern Doctor
关键词
纳洛酮
醒脑静
Ⅱ型呼吸衰竭
Naloxone
Xingnaojing
Type Ⅱ respiratory failure
