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孕激素防治早产研究 被引量:3

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摘要 早产是指妊娠满28周至不满37足周间发生分娩,是新生儿死亡和出现各种近远期并发症的主要原因。既往研究已经证实,在孕中期经阴道超声证实宫颈缩短的孕妇,早产的发生率增高。在这类孕妇中预防性使用孕激素可以预防早产的发生,但其在双胎妊娠中使用无效。目前已有研究提示,孕激素可能是通过抑制宫颈炎症反应,从而进一步抑制宫颈成熟来达到预防早产的作用。但明确的作用机制目前仍不清楚,有待进一步研究。
作者 向心力 段涛
出处 《现代妇产科进展》 CSCD 2013年第3期225-227,230,共4页 Progress in Obstetrics and Gynecology
基金 国家自然科学基金资助项目(No:81170628) 上海卫生新百人计划(No:XBR2011064)
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  • 1Campbell S. Universal cervical-length screening and vagi- nal progesterone prevents: early preterm births, reduces neonatal morbidity and is cost saving: doing nothing is no longer an option [ J ]. Ultrasound Obstet Gynec01,2011,38 (1):1-9.
  • 2Goldenberg RL, Culhane,JF, Iams JD,et al. Epidemiology and causes of preterm .birth [ J ]. Lancet, .2008, 371 (9606) : 75-84.
  • 3Laws PJ, Graylon N, Sullivan EA. Australia's mothers and babies 2004 [ M ]. Sydney : Australian Institute: of Health and Welfare, National Perinatal Statistics Unit ,2006.
  • 4Russell R, Green N, Steiner C, et al. Cost of hospitalization for preterm and low birth weight infants ir: the United States [ J]. Pediatrics ,2007,120( 1 ) :el -e9.
  • 5Behrman RE, Butler AS, Preterm Birth Causes l Conse- quences, and Prevention [ M]. Washington D. C. : The National Academies Press,2007.
  • 6Csapo AI. Progesterone "block" [ J]. Am Anat, 1956,98 (2) :273-291.
  • 7Oh SY, Kim C J, Park I, et al. Progesterone receptor isoform (A/B) ratio of human fetal membranes increases during term parturition [ J ]. Am j Obstet Gynecol,2005,193 ( 3 ) :1156-1160.
  • 8Mesiano S. Myometrial progesterone responsiveness and the control of human parturition [ J ]. J Soc Gynecol Inves- tig, 2004,11 ( 4 ) : 193-202.
  • 9Goldstein P, Berrier J, Rosen S, et al. A meta-analysis of randomized control trials of progestational agents in preg- nancy [ J ]. Br J Obstet Gynaecol, 1989,96 ( 3 ) : 265-274.
  • 10To MS, Skentou CA, Royston P, et al. Prediction of pa- tient-specific risk of early preterm delivery using mater- nal history and sonographic measurement of cervical length: a population-based prospective study [ J ]. Uhra- sound Obstet Gynecol,2006,27(4) :362-367.

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