摘要
目的研究阿奇霉素联合糖皮质激素治疗小儿支原体肺炎的临床疗效。方法选择支原体肺炎患儿124例，随机分为研究组和对照组，每组62例。在进行常规对症治疗的基础上，对照组给予阿奇霉素，剂量为10mg·kg^-1·d^-1。研究组在治疗前5d合用阿奇霉素与氢化可的松琥珀酸钠（剂量为0．2mg／kg），5d后停用氢化可的松琥珀酸钠，总疗程为2周。结果研究组患儿咳嗽、发热和肺部哕音消失时间明显短于对照组。研究组有效率为95．2％，对照组为83．9％，差异有统计学意义（P〈0．05）。研究组有9例患儿出现不良反应，对照组为14例，差异有统计学意义（P〈0．05）。结论糖皮质激素联合阿奇霉素治疗小儿肺炎支原体肺炎，可提高治疗疗效，缩短治疗时间，是小儿肺炎支原体肺炎临床治疗的较好选择。
Objective To investigate the clinical effects of azithromycin combined with glucocorticoid for the mycoplasma pneumonia in children. Methods 124 children with mycoplasma pneumonia were randomly divided into the study group and the control group with 62 cases in each group. On the basis of the routine symptomatic treatment, the control group was given azithromycin（ 10mg ·kg^-1·d^-1 ） and the study group was treated with azithromycin and hydrocortisone sodium succinate （0.2mg/kg） in the first five days, then stop giving hydrocortisone sodium succinate. The total course was two weeks. Results The study group of children with cough, fever and pulmonary rales disap- peared significantly shorter than the control group. Comparison of clinical efficacy, the study group effective rate was 95.2%, the control group was 83.9%, the difference was statistically significant （P 〈 0. 05 ）. Study group had 9 cases of adverse reactions, the control group had 14 cases of adverse reactions, the difference was statistically significant （P 〈 0.05 ）. Conclusion Glucocorticoid combined with azithromycin is used to treat children with mycoplasma pneumoniae pneumonia,which can improve the therapeutic efficacy and shorten treatment time. It is a better choice of clinical treatment for mycoplasma pneumoniae pneumonia in children.
出处
《中国基层医药》
CAS
2013年第8期1162-1163,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
肺炎
支原体
阿奇霉素
糖皮质激素
儿童
Pneumonia, mycoplasma
Azithromycin
Glucocorticoid
ChiIdren,
