摘要
目的针对1例诊断为晚期转移性肾癌患者,借助循证医学的方法进行证据检索和评价,以期找到更合适及有效的治疗方法。方法充分评估患者情况后,提出临床问题,检索Cochrane图书馆(2011年第4期)、Pubmed(1991-2011年)、中国学术期刊全文数据库(1991-2011年)等、万方数据库(1991-2011年)等。查找治疗晚期转移性肾癌有关的系统评价、临床随机对照试验等,并对所获证据进行评价。结果纳入符合要求的的随机对照试验25篇,系统评价或Meta分析23篇,根据所获证据给患者制定治疗方案。结论以高质量证据、结合患者情况制定治疗方案,能明显提高晚期转移性肾癌患者的近期疗效,但远期预后尚需更长时间的随访观察。
Objective In orde to find more appropriate and effective treatment for a patient with metastatic carcionma,we use the methods of evidence-based medicine to retrieve and evaluate literature. Method After a full assessment of the patient,we attempted to get the evidence of methods which are used to treat metastatic carcionma by searching Pubmed（1991-2011） 、 The Cochrane Library（Issue 4,2011） 、CNKI（1991-2011）、WANFANG Datebase（1991-2011）. Results A total of 25 randomized controlled trials,23 systematic reviews and meta-analyses were identified.The treatment plan was developed accordingly. Conclusion The individualized treatment plan based on the high quality evidence and patients condition was optimal for the short-term treatment of metastatic carcionma.However,the long-term prognostic benefitsneeded to be confirmed by continuing follow-up.
出处
《九江学院学报（自然科学版）》
CAS
2012年第3期98-101,111,共5页
Journal of Jiujiang University：Natural Science Edition
关键词
肾细胞癌
转移癌
免疫治疗
生物治疗
循证治疗
renal cell carcinoma
metastatic carcionma chemoimmunotherapy
biological treatment
evidence-Based Treatment
