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腹水miRNA-497、miRNA-936测定在胃癌性腹水腹腔化疗联合全身靶向治疗中的意义 被引量：5

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摘要 目的探讨腹水中miRNA-497、miRNA-936水平对于胃癌性腹水患者疗效评估及预后判断的价值。方法检测治疗组(给予腹腔化疗联合全身靶向治疗)21例和对照组(仅给予腹腔化疗)30例患者腹水中miRNA-497、miRNA-936水平。结果治疗组和对照组腹水中miRNA-497、miRNA-936水平治疗后较治疗前均明显下降(P<0.05);治疗组治疗后腹水中miRNA-497、miRNA-936水平低于对照组(P<0.05)。治疗组有效率为38.10%,对照组有效率16.67%(P<0.05)。结论胃癌性腹水腹腔化疗联合全身靶向治疗具有极其重要的潜在治疗价值,miRNA-497、miRNA-936在胃癌性腹水临床治疗中具有重要的疗效评估及预后判断的价值。
作者 项涛 雷慧
机构地区 广东医学院附属佛山市高明区人民医院肿瘤科 佛山市高明区中医院
出处 《肿瘤基础与临床》 2013年第2期142-144,共3页 journal of basic and clinical oncology
关键词 胃癌 腹水 miRNA-497 miRNA-936 腹腔化疗 全身靶向治疗
分类号 R735.2 [医药卫生—肿瘤] R730.6 [医药卫生—肿瘤]
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参考文献13

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同被引文献57

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肿瘤基础与临床
2013年 第2期

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