摘要
目的研究卒中后抑郁(PSD)2周及3个月的患病率与相关因素。方法对257例急性卒中患者进行2周及3个月前瞻性随访,调查卒中2周及3个月PSD患病率及相关因素。结果卒中2周PSD患病率为32.59%,其中轻型抑郁20.92%,重型抑郁11.67%。卒中3个月PSD患病率为42.68%,其中轻型抑郁19.87%,重型抑郁22.81%。卒中2周PSD相关因素是人格特质中的内向特质(P=0.000)、是否合并有糖尿病(P=0.000)及神经功能缺损评分(P=0.000)。卒中3个月PSD相关因素是急性期已经诊断PSD(P=0.000)及前循环卒中(P=0.04)。结论 PSD患病率较高。卒中2周PSD发生与内向人格特质、合并糖尿病及神经缺损有关,3个月发生与急性期PSD及前循环卒中有关。
Objective To study the prevalence of depression at 2 weeks and 3 months after stroke and relevant factors of post stoke depression. Methods Two hundreds and fifty-seven patients with acute stroke were prospectively followed at 2 weeks and 3 months after stroke. Results Depressive rate 2 weeks after stroke was 32.59%, with a minor depression rate of 20.92%, and a major depression rate of 11.67%. Post stroke depression rate was 42.68% 3 months after stroke, including minor depression of 19.87% and major depression of 22.81%. Independent relevant factors for post stroke depression 2 weeks after stroke included introversion personality （P = 0.000）, diabetes （ P = 0.000）, and severe neurologic impairment （ P = 0.000）. Independent relevant factors for post stroke depression 3 months after stroke included depression diagnosed at the acute stage （ P = 0.000） and anterior circulation stroke （ P = 0.04）. Conclusions Depression rate after stroke is high. Depression at 2 weeks after stroke is associated with introversion personality, severe neurologic impairment and diabetes. The independent relevant factors for depression at 3 months after stroke are depression diagnosed at the acute stage and anterior circulation stroke.
出处
《国际神经病学神经外科学杂志》
2013年第1期18-23,共6页
Journal of International Neurology and Neurosurgery
基金
2010-2011年度上海市第九人民医院院级基金(JY2011B08)
关键词
脑卒中
卒中后抑郁
患病率
相关因素
stroke
post stroke depression
prevalence
relevant factor
