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肝移植后新发自身免疫性肝炎一例诊疗体会 被引量：4

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摘要 肝移植后新发自身免疫性肝炎是指非自身免疫性肝病患者接受肝移植后新发生的自身免疫性肝炎，可导致肝纤维化和肝硬化，使移植肝功能丧失。这个概念首先由Kerkar等[1]于1998年提出，目前国内仅报道过2例[2]。2011年我中心收治1例肝移植后新发自身免疫性肝炎，现报告如下。
作者 陈虹 王旭 范铁艳 李俊 沈中阳
机构地区 武装警察部队总医院
出处 《中华器官移植杂志》 CAS CSCD 北大核心 2013年第4期248-249,共2页 Chinese Journal of Organ Transplantation
关键词 自身免疫性肝炎 移植后 诊疗 肝病患者 肝纤维化 功能丧失 肝硬化 移植肝
分类号 R657 [医药卫生—外科学]
  • 相关文献

参考文献9

  • 1Kerkar N, Hadzig N, Davies ET, et al. De-novo autoimmune hepatitis after liver transplantation. Lancet, 1998, 351 (9100) : 409-413.
  • 2张福奎,贾继东,张涛,王宇,崔焱,赵新颜,石晓燕,王泰龄,王宝恩.原发性胆汁性肝硬化患者肝移植后新发生自身免疫性肝炎二例分析[J].中华内科杂志,2006,45(11):930-931. 被引量：7
  • 3Fiel MI, Schiano TD. Plasma cell hepatitis ( de-novo autoimmune hepatitis) developing post liver transplantatioru Curr Opin Organ Transplant, 2012, 17(3):287-292.
  • 4Czaja AJ. Diagnosis, pathogenesis, and treatment of autoimmune hepatitis after liver transplantation. Dig Dis Sci, 2012, 57(9) :2248-2266.
  • 5Hennes EM, Zeniya M, Czaja AJ, et al. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology, 2008, 48 (1) : 169-176.
  • 6Salcedo M, Vaquero J, Ba ares R, et al. Response to steroids in de novo autoimmune hepatitis after liver transplantation. Hepatology, 2002, 35(2) :349-356.
  • 7Vierling JM. Diagnosis and treatment of autoimmune hepatitis. Curr Gastroenterol Rep, 2012, 14(1) :25-36.
  • 8Aguilera I, Sousa JM, Praena JM, et al. Choice of calcineurin inhibitor may influence the development of de novo immune hepatitis associated with anti - GSTT1 antibodies after liver transplantation. Clin Transplant, 2011, 25 (2) : 207-212.
  • 9Casanovas T, Argudo A, Pefia-Cala MC. Effectiveness and safety of everolimus in the treatment of autoimmune hepatitis related to anti - hepatitis C virus therapy after liver transplant: three case reports. Transplant Proc, 2011, 43(6):2233-2236.

二级参考文献7

  • 1Jones DE,James OF,Portmann B,et al.Development of autoimmune hepatitis following liver transplantation for primary biliary cirrhosis.Hepatology,1999,30:53-57.
  • 2Tan CK,Sian Ho JM.Concurrent de novo autoimmune hepatitis and recurrence of primary biliary cirrhosis post-liver transplantation.Liver Transpl,2001,7:461-465.
  • 3Tsuji H,Hiramatsu K,Minato H,et al.Auxiliary partial orthotopic liver transplantation with de novo autoimmune hepatitis in the allograft and leftover primary biliary cirrhosis in the native liver.Semin Liver Dis,2005,25:371-377.
  • 4Kerkar N,Hadzic N,Davies ET,et al.De-novo autoimmune hepatitis after liver transplantation.Lancet,1998,351:409-413.
  • 5Miyagawa-Hayashino A,Haga H,Egawa H,et al.Outcome and risk factors of de novo autoimmune hepatitis in living-donor liver transplantation.Transplantation,2004,78:128-135.
  • 6Heneghan MA,Portmann BC,Norris SM,et al.Graft dysfunction mimicking autoimmune hepatitis following liver transplantation in adults.Hepatology,2001,34:464-470.
  • 7Salcedo M,Vaquero J,Banares R,et al.Response to steroids in de novo autoimmune hepatitis after liver transplantation.Hepatology,2002,35:349-356.

共引文献6

同被引文献60

  • 1张福奎,贾继东,张涛,王宇,崔焱,赵新颜,石晓燕,王泰龄,王宝恩.原发性胆汁性肝硬化患者肝移植后新发生自身免疫性肝炎二例分析[J].中华内科杂志,2006,45(11):930-931. 被引量：7
  • 2宫川文.肝移植的病理.第43回日本病理学会近畿支部学术集会文集.2008.
  • 3Harada K, Hsu M, Ikeda H, et al. Application and validation of a new histologic staging and grading system for primary biliary cirrhosis [ J ]. J Clin Gastroenterol, 2013, 47 (2): 174-181.
  • 4Kakuda Y, Harada K, Sawada-Kitamura S, et al. Evaluation of a new histologic staging and grading system for primary biliary cirrhosis in comparison with classical systems[J]. HumPathol, 2013, 44 (6): 1107-1117.
  • 5Carbone M, Neuberger JM. Autoimmune liver disease, autoimmunity and liver transplantation [ J]. J Hepatol, 2014, 60 (1): 210-223.
  • 6Singal AK, Guturu P, Hmoud B, et al. Evolving frequency and outcomes of liver transplantation based on etiology of liver disease [ J ]. Transplantation, 2013, 95 (5) : 755-760.
  • 7Goldberg DS, Camp A, Martinez-Camacho A, et al. Risk of waitlist mortality in patients with primary sclerosing cholangitis and bacterial cholangitis [ J ]. Liver Transpl, 2013, 19 (3): 250-258.
  • 8Kazma I, Lemoine R, Herr F, et al. Mycophenolic acid- treated dendritic cells generate regulatory CD4^ + T cells that suppress CD8^ + T cells' allocytotoxicity [ J ] . Int Immunol, 2014, 26 (3): 173-181.
  • 9Jin X, Wang Y, Hawthorne WJ, et al. Enhanced suppression of the xenogeneic T-cell response in vitro by xenoantigen stimulated and expanded regulatory T cells [J]. Transplantation, 2014, 97 (1): 30-38.
  • 10Koga T, Ichinose K, Mizui M, et al. Calcium/ calmodulin-dependent protein kinase Ⅳ suppresses IL-2 production and regulatory T cell activity in lupus [ J]. J Immunol, 2012, 189 (7): 3490-3496.

引证文献4

二级引证文献7

中华器官移植杂志
2013年 第4期

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