摘要
目的:观察白内障超声乳化手术对不同年龄患者术后泪膜的影响,探讨其临床意义。方法:随机选取超声乳化白内障吸除联合人工晶状体植入术的患者154例(154只眼),按年龄分为3组,A组,患者年龄<60岁,共30只眼;B组,患者年龄为60～75岁,共68只眼;C组,患者年龄>75岁,共56只眼;3组患者均行10点位3mm角膜缘切口白内障超声乳化白内障吸除联合人工晶状体植入术。随访3个月,比较术后不同时间各组患者干眼症状评分、泪液分泌试验(SchirmerⅠ试验)、泪膜破裂时间(BUT)及角膜荧光素染色检查的变化。结果:术后7dA组患者干眼症状评分高于B和C组,差异有统计学意义(P<0.05或P<0.01);术后1和3个月,3组评分差异无统计学意义。术后7dC组患者SchirmerⅠ试验值低于A和B组,差异有统计学意义(P<0.01)。术后7dA组BUT长于B和C组,差异有统计学意义(P<0.01);术后1和3个月,C组患者BUT与A和B组比较差异有统计学意义(P<0.05或P<0.01);术后3个月C组患者BUT未恢复术前水平,差异有统计学意义(P<0.01)。术后7d和1个月A组患者角膜染色积分低于B和C组,差异有统计学意义(P<0.05或P<0.01);术后3个月,3组患者角膜染色积分比较差异无统计学意义。结论:不同年龄段患者白内障超声乳化手术后眼表损伤程度及恢复时间不同;高龄患者术后眼表损伤更大,恢复时间更长。
Objective To observe the effect of phacoemulsification surgery on tear film of the patients with different ages and to investigate the clinical significances.Methods 154 cases（154 eyes） with cataract accepted phacoemulsification combined with intraocular lens implantation were chosen and divided into three groups according to different ages：group A,30 eyes of the patients aged 60 years;group B,68 eyes of the patients aged 60-75 years;group C,56 eyes of the patients aged 75 years.Schirmer Ⅰ test,tear break-up time（BUT）,corneal fluorescein staining and dry eye symptom score were compared among three groups.Results 7 d after operation,the dry eye symptom score in group A was higher than those in groups B and C,there were significant differences（P0.05 or P0.01）;1 and 3 months after operation,the scores had no statistically significant differences between three groups.7 d after operation,the Schirmer Ⅰ test value in group C was lower than those in group A and B（P0.01）.7 d after operation,the BUT in group A was longer than those in group B and C,there were significant differences（P0.01）.1 and 3 months after operation,there were statistically significant differences between group C and group A,B（P0.05 or P0.01）.The BUT of the patients in group C didn＇t recover to preoperative level 3 months after operation（P0.01）.7 d and 1 month after operation,the corneal fluorescein staining score in group A was lower than those in group B and C,there were significant differences（P0.05 or P0.01）;3 months after operation,there were no statistically significant differences between three groups.Conclusion The injury degree and recovery time of ocular surface of the patients with different ages after phacoemulsification surgery are different;the injury of ocular surface after operation in elder patients is more serious and the recovery time is longer than the younger patients.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2013年第2期347-351,共5页
Journal of Jilin University：Medicine Edition
基金
吉林省科技厅科研基金资助课题(200905136)
