期刊文献+

异甘草酸镁防治药物性肝损伤的药理及临床研究进展 被引量:43

Progress in the Pharmacological and Clinical Researches of Magnesium Isoglycyrrhizinate in Prevention and Treatment of Drug-induced Liver Injury
原文传递
导出
摘要 异甘草酸镁是第4代甘草酸制剂,所含有效成分是单一构型的18α-甘草酸。药理及临床研究均表明,异甘草酸镁可安全有效地用于防治药物性肝损伤,发挥保肝护肝作用。综述近年来有关异甘草酸镁防治药物性肝损伤的药理作用和机制以及临床应用研究进展,并探讨其用于防治药物性肝损伤的优势。 Magnesium isoglycyrrhizinate(MgIG) is the fourth generation of glycyrrhizic acid preparation, in which the active component is 18α-glycyrrhizic acid as a single epimer. The pharmacological and clinical researches have demonstrated its hepatoprotective effects on drug-induced liver injury. The recent research progress on the pharmacological action, mechanism and clinical use of MgIG in the prevention and treatment of drug-induced liver injury was reviewed and its advantages in the prevention and treatment were discussed.
作者 金雯彦 于锋
出处 《药学进展》 CAS 2013年第4期161-166,共6页 Progress in Pharmaceutical Sciences
关键词 异甘草酸镁 药物性肝损伤 保肝护肝 药理作用 作用机制 临床应用 magnesium isoglycyrrhizinate drug-induced liver injury hepatoprotective effect pharmacological action mechanism of action clinical use
  • 相关文献

参考文献28

二级参考文献183

共引文献468

同被引文献382

引证文献43

二级引证文献214

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部