摘要
目的探讨感染性上尿路结石与上尿路感染发生的相关性。方法选择26例上尿路结石伴上尿路感染患者作为试验组，发热极期行血培养，碎石治疗之前行尿培养；选择30例上尿路结石未合并典型尿路感染症状患者作为对照组，常规行中段尿培养。两组结石排出后行成分分析及细菌培养。结果试验组血培养阳性4例，尿培养阳性23例，结石培养阳性18例，结石主要成分为六水磷酸镁铵，尿培养阳性标本与同一个体结石标本培养菌种一致的有13例。对照组尿培养阳性4例，结石培养阳性4例，成分以草酸钙结石、无水尿酸结石等非感染性结石为主。试验组感染性结石比例为69．2％（18／26），明显高于对照组的13．3％（4／30），尿培养阳性菌种与结石培养阳性菌种符合率为72．2％（13／18），明显高于对照组的25．0％（1／4），差异均有统计学意义（P〈0．05）。结论感染性上尿路结石是上尿路感染的主要原因，无水磷酸镁铵结石是最常见的感染性结石。
Objective To investigate the correlation between urinary calculi and upper urinary tract infections. Methods Twenty-six patients underwent lithiasis in upper urinary tract accompanied with infectious symptoms were enrolled in this study （test group）. Blood culture was obtained in peak temperature before lithotrity, urine sample was obtained for bacterial culture. Thirty patients with calculi in upper urinary tract accompanied no infectious symptoms in the same period were enrolled in control group. Calculi were pestled for bacterial culture and analyzed the components after the calculi were removed. Results In test group, the positive of blood, urine, calculi culture were 4, 23,18 patients. The prominent component of calculi was hexahydrate magnesium ammonium phosphate. Bacteria in 13 positive urine sample had the same property with the calculi samples which came from the same cases. In control group,the positive of urine, calculi culture were 4,4 patients. The prominent component of calculi were calcium oxalate calculi and uricite calculi. The morbidity of upper urinary tract infections in test group was significantly higher than that in control group [ 69.2% （18/26） vs. 13.3% （4/30） ] （P 〈 0.05 ）. The coincidence of urine culture and calculi culture in test group was significantly higher than that in control group [72.2%（13/18） vs. 25.0%（1/4） ]（P〈 0.05）. Conclusions Infectious calculi can easily result in upper urinary tract infections. Hexahydrate magnesium ammonium phosphate can make the prominent component in infectious calculi.
出处
《中国医师进修杂志》
2013年第11期6-8,共3页
Chinese Journal of Postgraduates of Medicine
基金
山西省科技攻关项目（20100312034）
关键词
尿路结石
主成分分析
泌尿道感染
细菌培养
Urinary calculi
Principal component analysis
Urinary tract infections
Bacterialculture
