摘要
目的:对宫颈癌根治术后有盆腔淋巴结转移的患者采用化疗加盆腔放疗,评价其治疗效果。方法:103例Ⅰb、Ⅱa期宫颈鳞癌行广泛性子宫切除加双侧盆腔淋巴结清扫术,术后病理检查有盆腔淋巴结转移者分两组,A组52例,BVP方案化疗加盆腔放疗;B组51例,单纯盆腔放疗。结果:五年生存率A、B两组分别为57.7％和49％,盆腔复发和远处转移分别是46.3％和52.9％,经统计学处理均无显著差异(P>0.05)。临床分期、盆腔淋巴结转移数目、合并脉管瘤栓与五年生存率也均无显著差异(P>0.05)。结论:BVP方案化疗加盆腔放疗与单纯盆腔放疗比较未能提高疗效与减少局部复发或远处转移。
Obsjective: To evaluate the curative effects of chemotherapy plus radiotherapy in the treatment of patients of cervi-cal cancer with pelvic lymph mode metastases after radical hysterectomy. Methods: 103 patients with stage I b and Ⅱ a squamous cell cervical cancer found to have pelvic lymph mode metastases after radical hysterectomy were divided into group A and group B. 52 pa-tients of group A were treated with the combination of chemotherapy (BVP regimen) and pelvic radiotherapy. 51 patients of group B were treated with pelvic radiotherapy alone. Results: The 5 - year overall survi al rate of A、B groups were 57.7% vs 49% respec-tively. Local recurrence or distant metastases were 46.3% vs 52.9% in two groups. There were all no significant difference (P > 0.05) . The 5 - year survi al rate with clinic stage number of pelvic lymph node comtaining metastases and lymph - vascular space in-vasion were all no significant difference in both groups ( P > 0.05) . Conclusion: Compared with pelvic radiotherapy alone, chemother-apy(BVP regime) plus pelvic radiotherapy can't elerate the curative effects and reduce local recurrence or distant metastases.
出处
《临床肿瘤学杂志》
CAS
2000年第1期39-40,共2页
Chinese Clinical Oncology
关键词
宫颈癌
淋巴转移
化疗
放射疗
预后
Cervical cancer Lymphatic metastasis Chemotherapy Radiotherapy Prognosis
