摘要
目的:评价我院抗癫痫药的应用情况与趋势。方法:采用世界卫生组织推荐的以限定日剂量(DDD)为指标的分析方法,对我院2005-2012年抗癫痫药的应用情况进行回顾性分析。结果:2005-2012年,托吡酯、卡马西平的销售金额逐渐下降,奥卡西平和左乙拉西坦的销售金额逐渐上升;用药频度(DDDs)排序列前2位的是卡马西平和苯巴比妥,奥卡西平的DDDs逐年上升,2012年已跃居至第1位;抗癫痫药的日均费用较稳定,但每种抗癫痫药的排序比值的变化各有不同。结论:我院目前临床上以传统抗癫痫药为主,但随着人们对新型抗癫痫药左乙拉西坦、奥卡西平等认识的加深,将来新型抗癫痫药的市场潜力巨大。
OBJECTIVE： To evaluate the utilization and tendency of antiepileptic drugs in our hospital. METHODS ： The utilization of antiepileptic drugs in our hospital from 2005 to 2012 were analyzed retrospectively by defined daily doses （DDD） recommended by WHO. RESULTS： The consumption sum of tipiramate and carbamazepine were decreasing during 2005--2012, while those of oxcarbazepine and levetiracetam were increasing. Top 2 drugs in the list of DDDs were carbamazepine and phenobarbital during 2005--2012, and that of oxcarbazepine increased year by year and leaped into the first place in 2012. During 2005--2012, the DDC of antiepileptic drugs was stable, but the variation of RM about antiepileptic drugs was different. CONCLUSIONS： The traditional antiepileptic drugs are dominant in our hospital, but the market potential of new antiepileptic drugs such as oxcarbaze- pine and levetiracetam will be huge as we know them more and more.
出处
《中国药房》
CAS
CSCD
2013年第18期1649-1651,共3页
China Pharmacy
