摘要
目的探讨血管扩张剂硝酸甘油舌下含服对多层螺旋CT(multi-slice spiral computed tomography,MSCT)冠状动脉成像质量的影响。方法 64例冠心病患者随机分为硝酸甘油组和对照组,硝酸甘油组在检查前舌下喷雾硝酸甘油约0.5 mg,对照组不用硝酸甘油,分别行MSCT和选择性冠脉造影(selective coronary arteriography,SCA),测定两组患者冠状动脉各血管节段管径,测量不同性质斑块处冠状动脉的狭窄程度及相关性。结果硝酸甘油组各血管节段管径较对照组明显扩张(P<0.05或P<0.01),各血管节段平均值硝酸甘油组也明显大于对照组(P<0.01)。两组两型斑块MSCT与SCA扫描测量结果平均值比较差异显著(P<0.01或P<0.05),对照组MSCT偏差分别为Ⅰ型斑块-10.11%(r=0.75,P<0.01)、Ⅱ型斑块+8.65%(r=0.89,P<0.01),硝酸甘油组MSCT偏差分别为Ⅰ型斑块+10.54%(r=0.73,P<0.01)、Ⅱ型斑块+16.37%(r=0.81,P<0.01)。结论硝酸甘油可明显扩张冠脉各节段血管,提高细小分支的显示率,提高MSCT对冠脉狭窄的诊断率,对于狭窄程度的评估有一定程度的偏高。
Objective To study the effects of nitroglycerin on coronary artery imaging quality of MSCT used in coronary disease.Methods 64 patients with＇ coronary disease were randomly di- vided into two groups： nitroglycerin group and control group. The nitroglycerin group was injec- ted sublingual nitroglycerin 0.5 mg,and the two groups were respectively performed MSCT and selective coronary angiography （SCA）, then the ascular segments and the stenosis degree and relevance of coronary artery in different plaques were examined. Results Compared with the control group, the diameter expansion of vascular segments in the nitroglycerin group was sig- nificant （P〈0.05 or P〈O.0t ）. The vascular segments average of the nitroglycerin group was sig- nificantly larger than that of the control group （P〈0.01）.The MSCT and SCA scanning meas- urement results of the two plaques in the two groups were significantly different （P〈0.01 or P 〈0.05 ）. The difference of MSCT in the control group was that the plaque type I was -10.11% （ r=0.75, P〈0.01） and plaque type II was ＋8.65% （r=0.89,P〈0.01）.The difference of MSCT in the nitroglycerin group was that the plaque type I was ＋10.54% （ r=0. 73,P〈0. 01） and plaque type 11 was ＋16.37% （r=0.81 ,P〈0.01）.Conclusions The nitroglycerin can make the ves- sels in coronary segments more obvious and improve the display rate of small branches and the diagnostic rate of MSCT on coronary artery stenosis. The evaluation of the degree of stenosis is a little high.
出处
《湖北民族学院学报（医学版）》
2013年第1期25-27,共3页
Journal of Hubei Minzu University(Medical Edition)
