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固有免疫在HIV感染中的作用研究

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摘要 易感人群对HIV的抵抗力及HIV感染者病情的发展取决于多种因素,包括病毒因素,如HIV病毒亚型和病毒载量等,以及宿主因素如接触途径、固有免疫系统和获得性免疫系统等。至今很少有人关注固有免疫在预防HIV病毒感染中的作用,但最近许多研究表明Toll样受体、自然杀伤细胞、IL-22,急性期淀粉样蛋白A和APOBEC3G等在抗HIV病毒感染中起关键作用。研究这些因子将揭示HIV病毒的发病机制,并有助于研发治疗这一类顽疾的新疗法。
出处 《首都公共卫生》 2013年第2期77-80,共4页 Capital Journal of Public Health
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