摘要
精子形态学分析可以评估精子受精能力和自发性受孕情况,尤其是精子头、颈和尾部的全面综合分析,结合患者的生活习惯、职业、临床表现等可以为患者的生育能力做出初步的诊断。精子形态学分析亦可用于评价精液样本处理的效果。尽管卵细胞质内单精子注射(ICSI)技术、活动精子细胞器形态学检查(MSOME)技术和胞质内形态学选择精子注射(IMSI)技术的应用可以使卵母细胞在不依赖于精子形态学和/或活动率的情形下受精,在一定程度上削弱了精子形态学分析的临床应用,但精子形态学分析的标准化操作和质量控制的实施不仅可以显著提高精子形态学分析结果的准确性,并可大大促进其在临床上的应用。因此,在临床男科实验室、生殖中心、精子库和检验科开展精子形态学分析很有必要,有一定的临床应用价值。
The analysis of sperm morphology can be used to evaluate sperm fertilizing ability and spontaneous conception status, and especially the overall analysis of the sperm head, neck and tail, along with the patient living habits, occupation and clinical mani- festations, may contribute to the primary diagnosis of the patient potentia generandi. It can also be employed to assess the effects of the treatment of semen samples, Although oocyte fertilization can be achieved by the technologies of intracytoplasmic sperm injection （ICSI）, motile sperm organelle morphology examination （MSOME） and intracytoplasmic morphologically selected sperm injection （IMSI） regardless of sperm morphology and / or motility, which may somewhat weaken the clinical application of sperm morphology analysis, the standardized procedure and the practice of quality control for the analysis of sperm morphology can significantly improve the accuracy of its results and largely promote its clinical application. Therefore, it is of positive necessity as well as clinical application value to perform sperm morphology analysis in andrology laboratories, reproductive centers, sperm banks and the department of laboratory medicine.
出处
《中华男科学杂志》
CAS
CSCD
2013年第4期291-295,共5页
National Journal of Andrology
关键词
精子形态学
卵细胞质内单精子注射
活动精子细胞器形态学检查
胞质内形态学选择精子注射
标准化
质量控制
sperm morphology
intracytoplasmic sperm injection
motile sperm organelle morphology examination
intracyto-plasmic morphologically selected sperm injection
standardization
quality control
