摘要
目的探讨隔姜灸不同灸量(艾炷大小7×9 mm,重50 mg,以3壮、6壮、9壮施灸于"神阙"穴,连续治疗3日)对局部效应与整体效应影响之间的相关性。方法建立急性高脂血症大鼠模型,观察隔姜灸3壮、6壮、9壮3种灸量刺激对大鼠施灸局部神阙穴皮肤间隙连接蛋白43(Cx43)表达的影响及与施灸温度、局部蛋白变性、血脂调节的相关性。结果隔姜灸各治疗组与模型对照组施灸局部Cx43表达差异无统计学意义(P>0.05),但各隔姜灸各治疗组对神阙穴局部Cx43表达的影响存在隔姜灸9壮>6壮>3壮的趋势。结论不同灸量隔姜灸穴位局部Cx43的表达与血脂调节、穴位局部温度变化、穴位局部蛋白质变性具有较为一致的相关性。
Objective To investigate the correlation between different amount of Ginger Moxibustion treatment（ moxa cone size of 7 mm × 9 mm,weight 50 nag, with 3 Zhuang,6 Zhuang,9 Zhuang moxibustion at Shenque point, for 3 consecutive days） on local effect and the overall effect. Methods The acute hyperlipidemia rat model was established to observe the effects of different dosage of moxibustion with ginger separated moxibustion on local Cx43 expression of experimental hyperlipidemia rats and the correlation with moxibustion temperature, local protein denaturation and blood lipid regulation. Results The differences between the local expression of Cx43 of ginger moxibustion treatment groups and model control group were not statistically significant （ P 〉 0. 05 ）, but the local Cx43 expression of Shenque point of gin-ger moxibustion treatment groups existed a trend as 9 Zhuang 〉 6 Zhuang 〉 3 Zhuang. Conclusions The effects of different dosage of moxi-bustion with ginger separated moxibustion of local Cx43 expression and the moxibustion temperature ,local protein denaturation and blood lipid regulation has a more consistent correlation.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2013年第8期1832-1834,共3页
Chinese Journal of Gerontology
基金
国家重点基础研究发展计划(973)项目(2009CB522905)
关键词
隔姜灸
灸量
缝隙连接蛋白43
高脂血症
Ginger separated moxibustion
Dosage of m0xibustion
Cx43
Hyperlipidemia
