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钙泊三醇倍他米松软膏治疗非泛发型白癜风的疗效观察 被引量:6

Effect of calcipotriol betamethasone ointment on treatment of non-generalized vitiligo
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摘要 目的观察钙泊三醇倍他米松软膏治疗非泛发型白癜风的临床疗效和安全性。方法 51例非泛发型白癜风患者外用钙泊三醇倍他米松软膏,每日1次涂于患处,连续使用3个月,每月1次观察临床疗效及不良反应。结果 51例患者中,痊愈8例,显效21例,好转10例,无效12例;显效率56.86%(29/51,复色面积≥50%),有效率76.47%(39/51,复色面积≥10%)。结论钙泊三醇倍他米松软膏治疗非泛发型白癜风安全、有效,不良反应小。 Objective To evaluate the therapeutic effect and safety of calcipotriol betarnethasone ointment on the treatment of non-generalized vitiligo. Methods Calcipotriol betarnethasone ointment was topically applied to the vitiliginous patches once daily in 51 patients with non-generalized vitiligo for 3 months, and the therapeutic effect and adverse effect were observed in each month. Results Of these 51 patients, 8 had complete repigmentation, 21 achieved excellent response, 10 experienced improvement, and the other 12 achieved almost no response. The excellent response rate was 56.86% (29/51, area of repigmentation ≥ 50%), and the effective rate was 76.47% (39/51, area of repigmentation ≥ 10%). Conclusion Calcipotriol betamethasone ointment is effective and safe in the treatment of vitiligo, with less adverse effect.
出处 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2013年第4期520-522,共3页 Journal of Shanghai Jiao tong University:Medical Science
关键词 白癜风 治疗 维生素D3 钙泊三醇倍他米松 vitiligo treatment vitmin D3 calcipotriol betamethasone
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  • 1王晓艳,王婷琳,周城,沈佚葳,丁晓岚,田珊,刘盈,彭光辉,周俊娥,薛树旗,王仁利,唐英,孟雪梅,裴广德,白云花,刘青,李航,杜娟,张建中.中国六省市白癜风流行病学调查[J].中华皮肤科杂志,2010,43(7):463-466. 被引量:32
  • 2樊建勇,杨慧兰.白癜风患者心理调查与结果分析[J].中国美容医学,2006,15(12):1390-1392. 被引量:7
  • 3黄褐斑和白癜风的诊疗标准(2010年版)[J].中华皮肤科杂志,2010,43(6):373-373. 被引量:425
  • 4Watabe H, Soma Y, Kawa Y, et al. Differentiation of murine mela- nocyte precursors induced by 1, 25-dihydroxyvitamin D3 is associated with the stimulation of endothelin B receptor expression[J].J Invest Dermatol, 2002, 119(3): 583-589.
  • 5Horikawa T, Norris DA, Johnson TW, et al. Dopa-negative melano- cytes in the outer root sheath of human hair follicles express premela- nosomal antigens but not a melanosomal antigen or the melansome- associated glycoprotein tyrosinase, TRP-I and TRP-2[J]. J Invest Dermatol, 1996, 106(1):28-35.
  • 6王大光,朱文元,鲁严,马慧军,岳学状,李诚让.1,25二羟基维生素D3对毛囊外毛根鞘无色素黑素细胞激活的实验研究[J].中国中西医结合皮肤性病学杂志,2010,9(6):338-340. 被引量:2
  • 7Seiter S, Ugurel S, Tilgen W, et al. Use of high-dose methylpred- nislone pulse therapy in patients with progressive and stable vitiligo [J]. Int J Dermatol, 2000, 39(8): 624 -627.
  • 8Kumaran MS, Kaur I, Kumar B. Effect of topical calcipotriol, beta- methasone dipropionate and their combination in the treatment of localized vitiligo [ J ]. J Eur Acad Dermatol Venereol, 2006, 20 (3): 269-273.

二级参考文献30

  • 1白癜风临床分型及疗效标准(2003年修订稿)[J].中华皮肤科杂志,2004,37(7):440-440. 被引量:801
  • 2王大光,朱文元,马慧军,李诚让,岳学状.淫羊藿苷抑制正常黑素细胞黑素合成的研究[J].临床皮肤科杂志,2004,33(8):460-462. 被引量:17
  • 3Njoo MD,Das PK,Bos JD,et al.Association of the Kobner phenomenon with disease activity and therapeutic responsiveness in vitiligo vulgaris.Arch Dermatol,1999,135(4):407-413.
  • 4Hamzavi I,Jain H,McLean D,et al.Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool:the Vitiligo Area Scoring Index.Arch Dermatol,2004,140(6):677-683.
  • 5Howitz J,Brodthagen H,Schwartz M,et al.Prevalence of vitiligo:epidemiological survey on the Isle of Bornholm,Denmark.Arch Dermatol,1977,113(1):47-52.
  • 6Bolognia JL,Pawelek JM.Biology of hypopigmentation.J Am Acad Dermatol,1988,19(2 Pt 1):217-255.
  • 7Boisseau-Garsaud AM,Garsaud P,Cales-Quist D,et al.Epidemiology of vitiligo in the French West Indies (Isle of Martinique).Int J Dermatol,2000,39(1):18-20.
  • 8Das SK,Majumder PP,Chakraborty R,et al.Studies on vitiligo.I.Epidemiological profile in Calcutta,India.Genet Epidemiol,1985,2(1):71-78.
  • 9Singh M,Singh G,Kanwar AJ,et al.Clinical pattern of vitiligo in Libya.Int J Dermatol,1985,24(4):233-235.
  • 10Lu T,Gao TW,Wang A,et al.Vitiligo prevalence study in Shanxi Province,China.Int J Dermatol,2007,46(1):47-51.

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