摘要
肝脏疾病是临床的常见病、多发病,在我国无论是相对发病率还是绝对病例数,肝脏疾病患者均居世界首位,是严重危害健康和耗费社会资源的主要疾病之一.近年来,国内外有关干细胞治疗慢性肝病的研究成果令人鼓舞,显示了勃勃生机.间充质干细胞是来源于发育早期中胚层的一类多能干细胞,研究证明他不仅存在于骨髓中,也存在于其他一些组织与器官的间质中,如外周血、脐血、松质骨、脂肪组织、滑膜和脐带等.本文就骨髓间充质干细胞、脐血间充质干细胞以及脐带间充质干细胞在治疗肝脏疾病方面的研究作一综述.
Liver diseases are common and frequent diseases that seriously affect human health and consume social resources. Both the absolute number of patients with liver diseases and their relative incidence in China are the highest in the world. In recent years, encouraging achievements have been achieved in stem cell therapy of chronic liver diseases both in China and abroad. Mesenchymal stem cells are a kind of pluripotent stem cells derived from the mesoderm. They exist not only in the bone marrow but also in other tissues, such as peripheral blood, umbilical cord blood, spongy bone, adipose tissue, synovium, and umbilical cord. In this article we review recent advances in the use of bone marrow mesenchymal stem cells, umbilical cord blood mesenchymal stem cells and umbilical cord mesenchymal stem cells for the treatment of liver diseases.
出处
《世界华人消化杂志》
CAS
北大核心
2013年第11期990-995,共6页
World Chinese Journal of Digestology
关键词
间充质干细胞
肝脏疾病
骨髓
脐血
脐带
Mesenchymal stem cells
Liver diseases
Bone marrow
Umbilical cord blood
Umbilical cord
